Cochrane Emergency Reviews

The Cochrane PEC has selected Cochrane Reviews devoted to pre-hospital and emergency medicine:

Our Reviews

Full list:

By subtopic:

EAR NOSE AND THROAT - STOMATOLOGY (86)
A spray containing ipratropium bromide administered into the nose to treat common cold symptoms
A spray containing ipratropium bromide administered into the nose to treat common cold symptoms
Acetaminophen (also called paracetamol) for the common cold in adults
Acetaminophen (also called paracetamol) for the common cold in adults
Antibiotic use for severe toothache (irreversible pulpitis)
Antibiotic use for severe toothache (irreversible pulpitis)
Antibiotics for acute middle ear infection (acute otitis media) in children
Antibiotics for acute middle ear infection (acute otitis media) in children
Antibiotics for otitis media with effusion ('glue ear') in children
Antibiotics for otitis media with effusion ('glue ear') in children
Antibiotics for people with sore throats
Antibiotics for people with sore throats
Antibiotics for sinus infection of short duration in adults
Antibiotics for sinus infection of short duration in adults
Antibiotics to treat adults with acute laryngitis
Antibiotics to treat adults with acute laryngitis
Antiviral drugs for sudden hearing loss (without known cause)
Antiviral drugs for sudden hearing loss (without known cause)
Antiviral treatment for Bell's palsy
Antiviral treatment for Bell's palsy
Corticosteroids as stand-alone or add-on treatment for sore throat
Corticosteroids as stand-alone or add-on treatment for sore throat
Corticosteroids for Bell's palsy
Corticosteroids for Bell's palsy
Decongestants, antihistamines and nasal irrigation for acute sinusitis in children
Decongestants, antihistamines and nasal irrigation for acute sinusitis in children
Different antibiotics for group A streptococcal pharyngitis
Different antibiotics for group A streptococcal pharyngitis
Do nasal decongestants used alone relieve cold symptoms?
Do nasal decongestants used alone relieve cold symptoms?
Dosage intervals of amoxicillin for the treatment of acute middle ear infection
Dosage intervals of amoxicillin for the treatment of acute middle ear infection
Drugs that prevent oral bleeding in people using oral anticoagulants undergoing minor oral surgery or dental extractions
Drugs that prevent oral bleeding in people using oral anticoagulants undergoing minor oral surgery or dental extractions
Glucocorticoids for croup in children
Glucocorticoids for croup in children
Helium-oxygen (heliox) treatment for children with croup
Helium-oxygen (heliox) treatment for children with croup
Hyperbaric oxygen as an additional treatment for malignant otitis externa
Hyperbaric oxygen as an additional treatment for malignant otitis externa
Hyperbaric oxygen for sudden hearing loss and tinnitus (ringing in the ears) of unknown cause
Hyperbaric oxygen for sudden hearing loss and tinnitus (ringing in the ears) of unknown cause
Influenza vaccine for preventing acute otitis media (middle ear infection)
Influenza vaccine for preventing acute otitis media (middle ear infection)
Interventions for treating traumatised permanent front teeth: luxated (dislodged) front teeth
Interventions for treating traumatised permanent front teeth: luxated (dislodged) front teeth
Intranasal corticosteroids for non-allergic rhinitis
Intranasal corticosteroids for non-allergic rhinitis
Modifications of the Epley manoeuvre for benign paroxysmal positional vertigo (BPPV)
Modifications of the Epley manoeuvre for benign paroxysmal positional vertigo (BPPV)
Nasal saline irrigation for acute upper airway infection symptoms
Nasal saline irrigation for acute upper airway infection symptoms
Nebulized epinephrine for croup in children
Nebulized epinephrine for croup in children
Needle aspiration compared to incision and drainage for the treatment of peritonsillar abscess (quinsy)
Needle aspiration compared to incision and drainage for the treatment of peritonsillar abscess (quinsy)
Pain relievers for children with acute middle ear infection
Pain relievers for children with acute middle ear infection
Pelargonium sidoides (Umckaloabo), a herbal remedy, for treating acute respiratory tract infections
Pelargonium sidoides (Umckaloabo), a herbal remedy, for treating acute respiratory tract infections
Positive pressure therapy for Ménière's disease or syndrome
Positive pressure therapy for Ménière's disease or syndrome
Sedation of children undergoing dental treatment
Sedation of children undergoing dental treatment
Steroidal anti-inflammatory medication given by mouth or injection for acute sinusitis
Steroidal anti-inflammatory medication given by mouth or injection for acute sinusitis
Steroids for acute sinusitis in adults and children
Steroids for acute sinusitis in adults and children
Steroids for the treatment of sudden hearing loss with unknown cause
Steroids for the treatment of sudden hearing loss with unknown cause
Systemic corticosteroids for improving symptoms in children with acute middle ear infection
Systemic corticosteroids for improving symptoms in children with acute middle ear infection
The effects of antibiotics on toothache caused by inflammation or infection at the root of the tooth in adults
The effects of antibiotics on toothache caused by inflammation or infection at the root of the tooth in adults
The Epley manoeuvre for benign paroxysmal positional vertigo (BPPV)
The Epley manoeuvre for benign paroxysmal positional vertigo (BPPV)
Topical antiseptics compared with antibiotics for people with chronic suppurative otitis media
Topical antiseptics compared with antibiotics for people with chronic suppurative otitis media
Tranexamic acid to help treat nosebleeds (epistaxis)
Tranexamic acid to help treat nosebleeds (epistaxis)
Use of rapid point-of-care testing for strep throat to guide doctors prescribing antibiotics for sore throat in primary care settings
Use of rapid point-of-care testing for strep throat to guide doctors prescribing antibiotics for sore throat in primary care settings
Vestibular rehabilitation to improve dizziness, balance and mobility in patients with unilateral peripheral vestibular dysfunction
Vestibular rehabilitation to improve dizziness, balance and mobility in patients with unilateral peripheral vestibular dysfunction
What is the performance of rapid tests for the diagnosis of strep throat in children?
What is the performance of rapid tests for the diagnosis of strep throat in children?
ANESTHESIA AND PAIN CONTROL (73)
ANESTHESIA (24)
A comparison of a local anaesthetic injection below the collarbone with other injection techniques for providing anaesthesia of the lower arm
A comparison of a local anaesthetic injection below the collarbone with other injection techniques for providing anaesthesia of the lower arm
Clonazepam for neuropathic pain and fibromyalgia in adults
Clonazepam for neuropathic pain and fibromyalgia in adults
Clonidine, lofexidine, and similar medications for the management of opioid withdrawal
Clonidine, lofexidine, and similar medications for the management of opioid withdrawal
Comparison of propofol (an anaesthetic drug) with other drug options for sedating people undergoing painful procedures in emergency departments
Comparison of propofol (an anaesthetic drug) with other drug options for sedating people undergoing painful procedures in emergency departments
Comparison of two muscle relaxants, rocuronium and succinylcholine, to facilitate rapid sequence induction intubation
Comparison of two muscle relaxants, rocuronium and succinylcholine, to facilitate rapid sequence induction intubation
Dexmedetomidine and clonidine for long-term sedation during mechanical ventilation in critically ill patients
Dexmedetomidine and clonidine for long-term sedation during mechanical ventilation in critically ill patients
Different methods of ventilation (controlling pressure vs volume) for people with acute respiratory failure due to lung injury
Different methods of ventilation (controlling pressure vs volume) for people with acute respiratory failure due to lung injury
Etomidate for sedating critically ill people during emergency endotracheal intubation
Etomidate for sedating critically ill people during emergency endotracheal intubation
Lidocaine for reducing propofol-induced pain on anaesthesia in adults
Lidocaine for reducing propofol-induced pain on anaesthesia in adults
Midazolam for sedation before procedures
Midazolam for sedation before procedures
Topical antibiotics to help reduce death and respiratory infections in people in intensive care receiving mechanical ventilation
Topical antibiotics to help reduce death and respiratory infections in people in intensive care receiving mechanical ventilation
Ultrasound guidance for injecting local anaesthetics in children to block pain transmission
Ultrasound guidance for injecting local anaesthetics in children to block pain transmission
PAIN CONTROL (49)
Caffeine as an analgesic adjuvant for acute pain in adults
Caffeine as an analgesic adjuvant for acute pain in adults
Clonazepam for neuropathic pain and fibromyalgia in adults
Codeine, alone and with paracetamol (acetaminophen), for cancer pain
Codeine, alone and with paracetamol (acetaminophen), for cancer pain
Corticosteroids for preventing postherpetic neuralgia
Corticosteroids for preventing postherpetic neuralgia
Do painkillers rubbed on the skin really work?
Do painkillers rubbed on the skin really work?
Drug treatments for pain in children and young people with life-limiting conditions
Drug treatments for pain in children and young people with life-limiting conditions
Drugs other than those used for epilepsy for treating trigeminal neuralgia
Drugs other than those used for epilepsy for treating trigeminal neuralgia
Haloperidol for the treatment of nausea and vomiting in palliative care patients
Haloperidol for the treatment of nausea and vomiting in palliative care patients
Intranasal fentanyl for the treatment of children in acute pain
Intranasal fentanyl for the treatment of children in acute pain
Local anaesthesia (numbing medicine) that is directly applied to the skin can provide pain control for repair of skin lacerations
Local anaesthesia (numbing medicine) that is directly applied to the skin can provide pain control for repair of skin lacerations
Local and regional anaesthesia at the time of surgery to prevent longer-term persistent pain after surgery
Local and regional anaesthesia at the time of surgery to prevent longer-term persistent pain after surgery
Medically assisted hydration to assist palliative care patients
Medically assisted hydration to assist palliative care patients
Morphine for neuropathic pain in adults
Morphine for neuropathic pain in adults
Oral nonsteroidal anti-inflammatory drugs (NSAIDs) for neuropathic pain in adults
Oral nonsteroidal anti-inflammatory drugs (NSAIDs) for neuropathic pain in adults
Oral painkillers available without prescription for acute pain
Oral painkillers available without prescription for acute pain
Sedation medication for relieving symptoms at the end of life
Sedation medication for relieving symptoms at the end of life
Skin-to-skin care with newborns cuts down procedural pain
Skin-to-skin care with newborns cuts down procedural pain
Sucrose for analgesia (pain relief) in newborn infants undergoing painful procedures
Sucrose for analgesia (pain relief) in newborn infants undergoing painful procedures
Sweet taste to ease injection needle pain in children aged one to 16 years
Sweet taste to ease injection needle pain in children aged one to 16 years
Topical non-steroidal anti-inflammatory drugs for acute musculoskeletal pain in adults
Topical non-steroidal anti-inflammatory drugs for acute musculoskeletal pain in adults
Transcutaneous Electrical Nerve Stimulation (TENS) to treat acute pain in adults
Transcutaneous Electrical Nerve Stimulation (TENS) to treat acute pain in adults
Treatment for jellyfish stings
Treatment for jellyfish stings
Treatments for high altitude (mountain) illness
Treatments for high altitude (mountain) illness
Vapocoolants (cold spray) for pain treatment during intravenous cannulation
Vapocoolants (cold spray) for pain treatment during intravenous cannulation
What are the benefits and risks of using virtual reality in a healthcare setting to distract children from pain?
What are the benefits and risks of using virtual reality in a healthcare setting to distract children from pain?
BLOOD DISORDERS AND CANCER (69)
CANCER (15)
Antibiotics to prevent bacterial infections due to chemotherapy in cancer patients with a low white blood cell count and no fever
Calcitonin used to treat metastatic bone pain
Calcitonin used to treat metastatic bone pain
Corticosteroids for the management of cancer-related breathlessness in adults with cancer
Corticosteroids for the management of cancer-related breathlessness in adults with cancer
Early palliative care for adults with advanced cancer
Early palliative care for adults with advanced cancer
Oral antibiotics for treating febrile neutropenia in cancer patients at low risk for complications
Oral antibiotics for treating febrile neutropenia in cancer patients at low risk for complications
Outpatient treatment for cancer patient with low-risk febrile neutropaenic event is effective.
Outpatient treatment for cancer patient with low-risk febrile neutropaenic event is effective.
Spectrum of the initial antibiotic treatment for cancer patients with fever and low leucocytes counts
Spectrum of the initial antibiotic treatment for cancer patients with fever and low leucocytes counts
Stopping antibiotic therapy early versus continuing until normal neutrophil count in people with cancer with fever and low neutrophil counts
Stopping antibiotic therapy early versus continuing until normal neutrophil count in people with cancer with fever and low neutrophil counts
SICKLE CELL DISEASE (26)
Antibiotics for treating acute chest syndrome in people with sickle cell disease
Antibiotics for treating acute chest syndrome in people with sickle cell disease
Antibiotics for treating osteomyelitis in people with sickle cell disease
Antibiotics for treating osteomyelitis in people with sickle cell disease
Antibiotics for treating pneumonia caught outside of hospital or care homes in people with sickle cell disease
Antibiotics for treating pneumonia caught outside of hospital or care homes in people with sickle cell disease
Blood transfusions for people with sickle cell disease before they undergo surgery
Blood transfusions for people with sickle cell disease before they undergo surgery
Blood transfusions for treating acute chest syndrome in people with sickle cell disease
Blood transfusions for treating acute chest syndrome in people with sickle cell disease
Inhaled drugs for opening up the airways in cases of acute chest syndrome in people with sickle cell disease
Inhaled drugs for opening up the airways in cases of acute chest syndrome in people with sickle cell disease
Inhaled nitric oxide for treating pain crises in people with sickle cell disease
Inhaled nitric oxide for treating pain crises in people with sickle cell disease
Long-term blood transfusions to prevent a stroke in people with sickle cell disease
Long-term blood transfusions to prevent a stroke in people with sickle cell disease
Low-molecular-weight heparins for pain caused by obstruction of blood vessels in people with sickle cell disease
Low-molecular-weight heparins for pain caused by obstruction of blood vessels in people with sickle cell disease
Magnesium for treating sickle cell disease
Magnesium for treating sickle cell disease
Piracetam for reducing the incidence of painful sickle cell disease crises
Piracetam for reducing the incidence of painful sickle cell disease crises
Replacing fluids to treat acute episodes of pain in people with sickle cell disease
Replacing fluids to treat acute episodes of pain in people with sickle cell disease
Treatments for long-lasting and painful erection of the penis in boys and men with sickle cell disease
Treatments for long-lasting and painful erection of the penis in boys and men with sickle cell disease
BLOOD DISORDERS-OTHER (28)
Alternative or additional agents to platelet transfusions to prevent bleeding in people with blood cancers receiving intensive treatment
Alternative or additional agents to platelet transfusions to prevent bleeding in people with blood cancers receiving intensive treatment
Antibiotics to prevent bacterial infections due to chemotherapy in cancer patients with a low white blood cell count and no fever
Antibiotics to prevent bacterial infections due to chemotherapy in cancer patients with a low white blood cell count and no fever
Antifibrinolytics (tranexamic acid and epsilon-aminocaproic acid) to prevent bleeding in people with low platelets due to bone marrow failure
Antifibrinolytics (tranexamic acid and epsilon-aminocaproic acid) to prevent bleeding in people with low platelets due to bone marrow failure
Different doses of platelet transfusion for preventing bleeding in people with low platelet counts due to treatment-induced bone marrow failure
Different doses of platelet transfusion for preventing bleeding in people with low platelet counts due to treatment-induced bone marrow failure
Is it safe to use lower blood counts as a trigger for blood transfusion in order to give fewer blood transfusions?
Is it safe to use lower blood counts as a trigger for blood transfusion in order to give fewer blood transfusions?
Plasma transfusions prior to insertion of lumbar puncture needles for people with abnormal coagulation
Plasma transfusions prior to insertion of lumbar puncture needles for people with abnormal coagulation
Platelet transfusion before surgery for people with low platelet counts
Platelet transfusion before surgery for people with low platelet counts
Platelet transfusions are used to prevent bleeding in patients with low platelet counts due to treatment-induced bone marrow failure
Platelet transfusions are used to prevent bleeding in patients with low platelet counts due to treatment-induced bone marrow failure
Platelet transfusions are used to prevent bleeding in people with low platelet counts due to treatment-induced bone marrow failure
Platelet transfusions are used to prevent bleeding in people with low platelet counts due to treatment-induced bone marrow failure
Platelet transfusions to treat bleeding compared with platelet transfusions to prevent bleeding in people with blood cancers receiving intensive treatment
Platelet transfusions to treat bleeding compared with platelet transfusions to prevent bleeding in people with blood cancers receiving intensive treatment
Prothrombin complex concentrate for reversal of vitamin K antagonist treatment in bleeding and non-bleeding patients
Prothrombin complex concentrate for reversal of vitamin K antagonist treatment in bleeding and non-bleeding patients
Recombinant (non-human) factor VIIa clotting factor concentrates versus plasma concentrates for acute bleeds in people with haemophilia and inhibitors
Recombinant (non-human) factor VIIa clotting factor concentrates versus plasma concentrates for acute bleeds in people with haemophilia and inhibitors
The optimal warfarin dose for patients beginning therapy
The optimal warfarin dose for patients beginning therapy
Treatments for acute bleeds in people with acquired hemophilia A
Treatments for acute bleeds in people with acquired hemophilia A
EDUCATION (16)
EDUCATION-OTHER (12)
Do education and training programs reduce aggressive behavior toward healthcare workers?
Do education and training programs reduce aggressive behavior toward healthcare workers?
Interventions to promote informed consent for patients undergoing surgical and other invasive healthcare procedures
Interventions to promote informed consent for patients undergoing surgical and other invasive healthcare procedures
Printed educational materials for healthcare professional practice and patient health
Printed educational materials for healthcare professional practice and patient health
Screening women for intimate partner violence in healthcare settings
Screening women for intimate partner violence in healthcare settings
The effects of interactive training of healthcare providers on the management of life-threatening emergencies in hospital
The effects of interactive training of healthcare providers on the management of life-threatening emergencies in hospital
Training interventions for improving telephone consultation skills in clinicians
Training interventions for improving telephone consultation skills in clinicians
SIMULATION (4)
Educational games to improve health care professional practice and care for patients
Educational games to improve health care professional practice and care for patients
Simulation-based obstetric team training to improve the overall outcome of obstetric health care
Simulation-based obstetric team training to improve the overall outcome of obstetric health care
EMERGENCY MEDICAL SYSTEM (EMS) MANAGEMENT - PUBLIC HEALTH - LEGAL MEDICINE (40)
EMERGENCY MEDICAL SYSTEM MANAGEMENT (32)
Are interventions to improve clinical incidence reporting effective?
Are interventions to improve clinical incidence reporting effective?
Audit and feedback: effects on professional practice and patient outcomes
Audit and feedback: effects on professional practice and patient outcomes
Comparing walk-in clinics to physician offices and emergency rooms
Comparing walk-in clinics to physician offices and emergency rooms
Discharge planning from hospital
Discharge planning from hospital
Health workers' perceptions and experiences of using mHealth technologies to deliver primary healthcare services: a qualitative evidence synthesis
Health workers' perceptions and experiences of using mHealth technologies to deliver primary healthcare services: a qualitative evidence synthesis
Helicopter emergency medical services for adults with major trauma
Helicopter emergency medical services for adults with major trauma
Home-based end-of-life care
Home-based end-of-life care
Improving how physicians working in hospital settings prescribe antibiotics
Improving how physicians working in hospital settings prescribe antibiotics
Mobile phone messaging for communicating results of medical investigations
Mobile phone messaging for communicating results of medical investigations
Primary care professionals providing non-urgent care in hospital emergency departments
Primary care professionals providing non-urgent care in hospital emergency departments
Programmes, policies and work practices that reduce aggression by patients towards healthcare workers
Programmes, policies and work practices that reduce aggression by patients towards healthcare workers
The effect of automatically generated reminders delivered to providers on paper on quality of care and patient outcomes
The effect of automatically generated reminders delivered to providers on paper on quality of care and patient outcomes
The effects of using email to send test results to patients
The effects of using email to send test results to patients
Using email for healthcare professionals to contact each other
Using email for healthcare professionals to contact each other
Using mobile technologies to promote communication and management of care between healthcare professionals
Using mobile technologies to promote communication and management of care between healthcare professionals
What are healthcare stakeholders’ perceptions and experiences of factors affecting the implementation of critical care telemedicine?
What are healthcare stakeholders’ perceptions and experiences of factors affecting the implementation of critical care telemedicine?
LEGAL MEDICINE (0)
PUBLIC HEALTH (8)
Adult patient access to electronic health records
Adult patient access to electronic health records
Conflicts of interest and recommendations in clinical guidelines, advisory committee reports, opinion pieces, and narrative reviews
Conflicts of interest and recommendations in clinical guidelines, advisory committee reports, opinion pieces, and narrative reviews
Does cleaning hands with ash stop or reduce the spread of viral and bacterial infections compared with soap or other materials?
Does cleaning hands with ash stop or reduce the spread of viral and bacterial infections compared with soap or other materials?
Patient-initiated appointments for people with chronic conditions managed in hospital outpatient settings
Patient-initiated appointments for people with chronic conditions managed in hospital outpatient settings
ETHICS - RESEARCH (18)
ETHICS (0)
RESEARCH (18)
Audio-visual presentation of information used in the informed consent process for people considering entering clinical trials
Audio-visual presentation of information used in the informed consent process for people considering entering clinical trials
Bias due to selective inclusion and reporting of outcomes and analyses in systematic reviews of randomised trials of healthcare interventions
Bias due to selective inclusion and reporting of outcomes and analyses in systematic reviews of randomised trials of healthcare interventions
Comparing effect estimates of randomized controlled trials and observational studies
Comparing effect estimates of randomized controlled trials and observational studies
Comparison of central adjudication of outcomes and onsite outcome assessment on treatment effect estimates
Comparison of central adjudication of outcomes and onsite outcome assessment on treatment effect estimates
CONsolidated Standards Of Reporting Trials (CONSORT) and the completeness of reporting of randomised controlled trials published in medical journals
CONsolidated Standards Of Reporting Trials (CONSORT) and the completeness of reporting of randomised controlled trials published in medical journals
Full publication of results initially presented in abstracts
Full publication of results initially presented in abstracts
Industry sponsorship and research outcome
Industry sponsorship and research outcome
New treatments versus established treatments in randomized trials
New treatments versus established treatments in randomized trials
Search strategies to identify diagnostic accuracy studies in MEDLINE and EMBASE
Search strategies to identify diagnostic accuracy studies in MEDLINE and EMBASE
ENDOCRINE AND METABOLIC (12)
DIABETES (10)
Alginate dressings for healing foot ulcers in people with diabetes mellitus
Alginate dressings for healing foot ulcers in people with diabetes mellitus
Antibiotics to treat foot infections in people with diabetes
Antibiotics to treat foot infections in people with diabetes
First aid glucose administration routes for symptomatic hypoglycaemia
First aid glucose administration routes for symptomatic hypoglycaemia
Hydrocolloid dressings to promote foot ulcer healing in people with diabetes when compared with other dressing types
Hydrocolloid dressings to promote foot ulcer healing in people with diabetes when compared with other dressing types
Subcutaneous rapid-acting insulin analogues for diabetic ketoacidosis
Subcutaneous rapid-acting insulin analogues for diabetic ketoacidosis
ENDOCRINE AND METABOLIC-OTHER (2)
Clinical symptoms, signs and tests for identification of impending and current water-loss dehydration in older people
Clinical symptoms, signs and tests for identification of impending and current water-loss dehydration in older people
GASTROENTEROLOGY (72)
DIGESTIVE BLEEDING (16)
Antifibrinolytic amino acids for upper gastrointestinal bleeding in people with acute or chronic liver disease
Antifibrinolytic amino acids for upper gastrointestinal bleeding in people with acute or chronic liver disease
Band ligation versus no intervention for primary prevention of upper gastrointestinal bleeding in people with cirrhosis and oesophageal varices
Band ligation versus no intervention for primary prevention of upper gastrointestinal bleeding in people with cirrhosis and oesophageal varices
Banding ligation versus beta-blockers for primary prevention in oesophageal varices in adults
Banding ligation versus beta-blockers for primary prevention in oesophageal varices in adults
Somatostatin analogues for acute bleeding oesophageal varices
Somatostatin analogues for acute bleeding oesophageal varices
Tranexamic acid, an agent that promotes blood clotting, for serious or uncontrolled upper gastrointestinal bleeding
Tranexamic acid, an agent that promotes blood clotting, for serious or uncontrolled upper gastrointestinal bleeding
Treatment for bleeding from enlarged veins in the oesophagus (food pipe) in people with advanced scarring of the liver
Treatment for bleeding from enlarged veins in the oesophagus (food pipe) in people with advanced scarring of the liver
Vitamin K for upper gastrointestinal bleeding in people with acute or chronic liver diseases
Vitamin K for upper gastrointestinal bleeding in people with acute or chronic liver diseases
What is the best regimen of proton pump inhibitors for bleeding peptic ulcers?
What is the best regimen of proton pump inhibitors for bleeding peptic ulcers?
HEPATITIS (2)
Glucocorticosteroids for people with alcoholic hepatitis
Glucocorticosteroids for people with alcoholic hepatitis
GASTROENTEROLOGY-OTHER (54)
Antibiotic therapy for Clostridium difficile-associated diarrhoea in adults
Antibiotic therapy for Clostridium difficile-associated diarrhoea in adults
Antibiotic treatment for spontaneous bacterial peritonitis in people with advanced liver disease
Antibiotic treatment for spontaneous bacterial peritonitis in people with advanced liver disease
Antibiotics for non-typhoidal Salmonella diarrhoea
Antibiotics for non-typhoidal Salmonella diarrhoea
Antibiotics for uncomplicated diverticulitis
Antibiotics for uncomplicated diverticulitis
Blood and urine tests for the diagnosis of acute pancreatitis (sudden inflammation of pancreas)
Blood and urine tests for the diagnosis of acute pancreatitis (sudden inflammation of pancreas)
Blood tests for the diagnosis of pancreatic necrosis (pancreatic destruction due to inflammation of pancreas)
Blood tests for the diagnosis of pancreatic necrosis (pancreatic destruction due to inflammation of pancreas)
Branched-chain amino acids improve symptoms of hepatic encephalopathy
Branched-chain amino acids improve symptoms of hepatic encephalopathy
Drug treatments that specifically target ammonia for adults with cirrhosis and hepatic encephalopathy
Drug treatments that specifically target ammonia for adults with cirrhosis and hepatic encephalopathy
Early or delayed surgical removal of appendix in people with symptomatic complicated appendicitis
Early or delayed surgical removal of appendix in people with symptomatic complicated appendicitis
Flumazenil versus placebo or no intervention for people with cirrhosis and hepatic encephalopathy
Flumazenil versus placebo or no intervention for people with cirrhosis and hepatic encephalopathy
Food-based oral rehydration solution for acute diarrhoea
Food-based oral rehydration solution for acute diarrhoea
How accurate is computed tomography for the diagnosis of acute appendicitis in adults?
How accurate is computed tomography for the diagnosis of acute appendicitis in adults?
Managing acute lower abdominal pain in women of childbearing age
Managing acute lower abdominal pain in women of childbearing age
Medical treatment for people with acute pancreatitis (sudden inflammation of the pancreas)
Medical treatment for people with acute pancreatitis (sudden inflammation of the pancreas)
Medicines in the treatment of emergency department nausea and vomiting
Medicines in the treatment of emergency department nausea and vomiting
Metoclopramide for accurate placement of naso-enteral feeding tube
Metoclopramide for accurate placement of naso-enteral feeding tube
N-acetylcysteine for acute liver failure not caused by paracetamol overdose
N-acetylcysteine for acute liver failure not caused by paracetamol overdose
Non-steroid anti-inflammatory drugs for biliary colic
Non-steroid anti-inflammatory drugs for biliary colic
Opioids for abdominal pain in acute pancreatitis
Opioids for abdominal pain in acute pancreatitis
Oral zinc supplementation for treating diarrhoea in children
Oral zinc supplementation for treating diarrhoea in children
Phlebotonics for haemorrhoids
Phlebotonics for haemorrhoids
Psychosocial therapy for recurrent abdominal pain in childhood
Psychosocial therapy for recurrent abdominal pain in childhood
Short-term treatment with medications for heartburn symptoms
Short-term treatment with medications for heartburn symptoms
The effect of removing or reducing lactose from milk in young children with acute diarrhoea
The effect of removing or reducing lactose from milk in young children with acute diarrhoea
Treatment of hepatorenal syndrome
Treatment of hepatorenal syndrome
Tube feeding in patients with acute pancreatitis
Tube feeding in patients with acute pancreatitis
Ultrasound and liver function tests for the diagnosis of common bile duct stones
Ultrasound and liver function tests for the diagnosis of common bile duct stones
GERIATRICS (0)
HEART AND CIRCULATION (192)
ARYTHMIA (16)
Adenosine versus intravenous calcium channel antagonists for tachycardia in adults
Adenosine versus intravenous calcium channel antagonists for tachycardia in adults
Antiarrhythmics for maintaining sinus rhythm (normal heartbeat) after reversing atrial fibrillation (correcting an irregular heartbeat)
Antiarrhythmics for maintaining sinus rhythm (normal heartbeat) after reversing atrial fibrillation (correcting an irregular heartbeat)
Benefits and harms of ablation for people with non-paroxysmal atrial fibrillation
Benefits and harms of ablation for people with non-paroxysmal atrial fibrillation
Comparing two types of blood-thinning drugs, factor Xa inhibitors and vitamin K antagonists, to prevent blood clots in people with atrial fibrillation
Comparing two types of blood-thinning drugs, factor Xa inhibitors and vitamin K antagonists, to prevent blood clots in people with atrial fibrillation
Direct oral anticoagulants for prevention of stroke in atrial fibrillation patients with chronic kidney disease
Direct oral anticoagulants for prevention of stroke in atrial fibrillation patients with chronic kidney disease
Direct thrombin inhibitors compared with vitamin K antagonists in people with atrial fibrillation for preventing stroke
Direct thrombin inhibitors compared with vitamin K antagonists in people with atrial fibrillation for preventing stroke
Screening people over 65 years of age for atrial fibrillation increases the rate of detection
Screening people over 65 years of age for atrial fibrillation increases the rate of detection
The effectiveness of the Valsalva Manoeuvre for stopping an abnormal heart rhythm
The effectiveness of the Valsalva Manoeuvre for stopping an abnormal heart rhythm
CARDIAC ARREST (22)
Active compression-decompression using a hand-held device for emergency heart massage
Active compression-decompression using a hand-held device for emergency heart massage
Adrenaline and vasopressin for cardiac arrest
Adrenaline and vasopressin for cardiac arrest
Aminophylline for cardiac arrest
Aminophylline for cardiac arrest
Community first responders for out-of-hospital cardiac arrest in adults and children
Community first responders for out-of-hospital cardiac arrest in adults and children
Continuous chest compression versus interrupted chest compression for cardiopulmonary resuscitation (CPR) of non-asphyxial out-of-hospital cardiac arrest (OHCA)
Continuous chest compression versus interrupted chest compression for cardiopulmonary resuscitation (CPR) of non-asphyxial out-of-hospital cardiac arrest (OHCA)
Cooling the body after resuscitation following cardiac arrest
Cooling the body after resuscitation following cardiac arrest
Lower versus higher oxygen concentrations titrated to target oxygen saturations during resuscitation of preterm infants at birth
Lower versus higher oxygen concentrations titrated to target oxygen saturations during resuscitation of preterm infants at birth
Mechanical chest compression machines for cardiac arrest
Mechanical chest compression machines for cardiac arrest
Should patients experiencing sudden cardiac death be cooled to lower their body temperature prior to or after admission to hospital?
Should patients experiencing sudden cardiac death be cooled to lower their body temperature prior to or after admission to hospital?
Therapeutic hypothermia as a neuroprotective therapy after cardiopulmonary arrest in children
Therapeutic hypothermia as a neuroprotective therapy after cardiopulmonary arrest in children
Type of electrical shock to restart the heart in a non-hospitalised person whose heart stops beating
Type of electrical shock to restart the heart in a non-hospitalised person whose heart stops beating
DEEP VEIN THROMBOSIS (34)
Blood thinners for the initial treatment of blood clots in people with cancer
Blood thinners for the initial treatment of blood clots in people with cancer
Fixed daily dose of a low molecular weight heparin compared with an adjusted dose of unfractionated heparin for treating blood clots in the deep veins
Fixed daily dose of a low molecular weight heparin compared with an adjusted dose of unfractionated heparin for treating blood clots in the deep veins
Harms and benefits of dissolving blood clots in deep blood vessels in the arms
Harms and benefits of dissolving blood clots in deep blood vessels in the arms
Home versus in-patient treatment for deep vein blood clots
Home versus in-patient treatment for deep vein blood clots
Interventions to increase the use of measures to prevent the development of blood clots in hospitalized medical and surgical patients
Interventions to increase the use of measures to prevent the development of blood clots in hospitalized medical and surgical patients
Length of treatment with vitamin K antagonists and prevention of recurrence in patients with venous thromboembolism
Length of treatment with vitamin K antagonists and prevention of recurrence in patients with venous thromboembolism
Novel oral anticoagulants for the treatment of deep vein thrombosis
Novel oral anticoagulants for the treatment of deep vein thrombosis
Once versus twice daily injections of low molecular weight heparin for the initial treatment of blood clots in the veins
Once versus twice daily injections of low molecular weight heparin for the initial treatment of blood clots in the veins
Pentasaccharides for the treatment of deep vein thrombosis
Pentasaccharides for the treatment of deep vein thrombosis
Pharmacomechanical thrombectomy for iliofemoral deep vein thrombosis
Pharmacomechanical thrombectomy for iliofemoral deep vein thrombosis
Subcutaneous unfractionated heparin for the initial treatment of venous thromboembolism
Subcutaneous unfractionated heparin for the initial treatment of venous thromboembolism
Thrombolysis for treatment of acute deep vein thrombosis
Thrombolysis for treatment of acute deep vein thrombosis
Thrombophilia testing for the prevention of recurrent venous thromboembolism
Thrombophilia testing for the prevention of recurrent venous thromboembolism
Treatment for superficial infusion thrombophlebitis of the upper extremity
Treatment for superficial infusion thrombophlebitis of the upper extremity
Treatment of below-the-knee deep vein thrombosis
Treatment of below-the-knee deep vein thrombosis
Vitamin K antagonists or low-molecular-weight heparin for long term treatment of symptomatic blood clots
Vitamin K antagonists or low-molecular-weight heparin for long term treatment of symptomatic blood clots
Warfarin initiation nomograms of 5 mg and 10 mg for venous thromboembolism
Warfarin initiation nomograms of 5 mg and 10 mg for venous thromboembolism
HEART FAILURE (16)
A breathing intervention for shortness of breath due to heart failure
A breathing intervention for shortness of breath due to heart failure
Antiplatelet versus anticoagulation treatment for patients with heart failure in sinus rhythm
Antiplatelet versus anticoagulation treatment for patients with heart failure in sinus rhythm
B-type natriuretic peptide-guided treatment for heart failure patients
B-type natriuretic peptide-guided treatment for heart failure patients
Digitalis for treatment of heart failure in patients in sinus rhythm
Digitalis for treatment of heart failure in patients in sinus rhythm
Disease management programmes for heart failure
Disease management programmes for heart failure
Natriuretic peptide-guided treatment for preventing death and cardiovascular events among patients with risk factors for heart disease
Natriuretic peptide-guided treatment for preventing death and cardiovascular events among patients with risk factors for heart disease
Nitrates for acute heart failure syndromes
Nitrates for acute heart failure syndromes
What is the evidence for the benefit and harms of anticoagulants for heart failure?
What is the evidence for the benefit and harms of anticoagulants for heart failure?
HYPERTENSION (18)
Benefits of antihypertensive drugs for mild hypertension are unclear
Benefits of antihypertensive drugs for mild hypertension are unclear
Beta-blockers for hypertension
Beta-blockers for hypertension
Blood pressure targets in people with cardiovascular disease
Blood pressure targets in people with cardiovascular disease
First-line diuretics versus other classes of antihypertensive drugs for hypertension (protocol stage)
First-line diuretics versus other classes of antihypertensive drugs for hypertension (protocol stage)
Partial agonists for the treatment of high blood pressure.
Partial agonists for the treatment of high blood pressure.
Renin angiotensin system inhibitors versus other types of medicine for hypertension
Renin angiotensin system inhibitors versus other types of medicine for hypertension
Stopping blood pressure medications in older people
Stopping blood pressure medications in older people
The use of lower blood pressure targets for people with hypertension
The use of lower blood pressure targets for people with hypertension
Thiazides best first choice for hypertension
Thiazides best first choice for hypertension
MYOCARDIAL ISCHEMIA/CORONARY DISEASE (28)
Benefits and harms of drug-eluting versus bare-metal stents in people with acute coronary syndrome
Benefits and harms of drug-eluting versus bare-metal stents in people with acute coronary syndrome
Beta-blockers versus placebo or no intervention for patients with suspected or diagnosed myocardial infarction
Beta-blockers versus placebo or no intervention for patients with suspected or diagnosed myocardial infarction
Coronary artery bypass surgery performed with versus without cardiac arrest and cardiopulmonary bypass in patients with ischaemic heart disease
Coronary artery bypass surgery performed with versus without cardiac arrest and cardiopulmonary bypass in patients with ischaemic heart disease
Delivering clot-busting therapy before reaching hospital or in hospital to help people who are having heart attacks
Delivering clot-busting therapy before reaching hospital or in hospital to help people who are having heart attacks
Does hyperbaric oxygen therapy improve outcome after heart attack?
Does hyperbaric oxygen therapy improve outcome after heart attack?
Drugs used as add-on therapy to heart procedure following heart attack
Drugs used as add-on therapy to heart procedure following heart attack
Inotropic and vasodilator strategies in people with cardiogenic shock or low cardiac output
Inotropic and vasodilator strategies in people with cardiogenic shock or low cardiac output
Intra-aortic balloon counterpulsation in patients with acute myocardial infarction and cardiogenic shock
Intra-aortic balloon counterpulsation in patients with acute myocardial infarction and cardiogenic shock
Platelet glycoprotein IIb/IIIa blockers during percutaneous coronary intervention and as the initial treatment of acute coronary syndromes
Platelet glycoprotein IIb/IIIa blockers during percutaneous coronary intervention and as the initial treatment of acute coronary syndromes
Prophylactic lidocaine for myocardial infarction
Prophylactic lidocaine for myocardial infarction
Routine invasive versus conservative strategies for unstable angina and non-ST elevation myocardial infarction in the stent era
Routine invasive versus conservative strategies for unstable angina and non-ST elevation myocardial infarction in the stent era
Routine use of oxygen in people who have had a heart attack
Routine use of oxygen in people who have had a heart attack
Stem cell treatment following a heart attack
Stem cell treatment following a heart attack
Xiongshao capsule preventing restenosis after percutaneous coronary intervention in patients with coronary heart disease
Xiongshao capsule preventing restenosis after percutaneous coronary intervention in patients with coronary heart disease
HEART AND CIRCULATION-OTHER (41)
Antithrombin III for critically ill patients
Antithrombin III for critically ill patients
Buffered solutions versus 0.9% saline for resuscitation in critically ill adults and children
Buffered solutions versus 0.9% saline for resuscitation in critically ill adults and children
Colloids or crystalloids for fluid replacement in critically people
Colloids or crystalloids for fluid replacement in critically people
D-dimer for excluding pulmonary embolism in hospital outpatient and accident and emergency populations
D-dimer for excluding pulmonary embolism in hospital outpatient and accident and emergency populations
Drugs to dissolve pulmonary embolism (blood clot in the lungs)
Drugs to dissolve pulmonary embolism (blood clot in the lungs)
Endovascular treatment for ruptured abdominal aortic aneurysm
Endovascular treatment for ruptured abdominal aortic aneurysm
Extracorporeal (external to the body) membrane oxygenation (ECMO) for critically ill adults
Extracorporeal (external to the body) membrane oxygenation (ECMO) for critically ill adults
Fluids for hydration in children
Fluids for hydration in children
Giving glutamine supplements to critically ill adults
Giving glutamine supplements to critically ill adults
Hormone treatment may be ineffective in treating people with viral myocarditis
Hormone treatment may be ineffective in treating people with viral myocarditis
Inotropic and vasodilator strategies in people with cardiogenic shock or low cardiac output
Loop diuretics cause modest blood pressure lowering
Loop diuretics cause modest blood pressure lowering
Mechanical heart pumps to aid a heart that fails suddenly
Mechanical heart pumps to aid a heart that fails suddenly
Novel oral anticoagulants (DOACs) for the treatment of pulmonary embolism
Novel oral anticoagulants (DOACs) for the treatment of pulmonary embolism
Outpatient versus inpatient treatment for acute pulmonary embolism
Outpatient versus inpatient treatment for acute pulmonary embolism
Surgery for small abdominal aortic aneurysms that do not cause symptoms
Surgery for small abdominal aortic aneurysms that do not cause symptoms
Systematic review of randomised controlled trials about the efficacy and safety of colchicine in people with pericarditis
Systematic review of randomised controlled trials about the efficacy and safety of colchicine in people with pericarditis
Treatment for superficial thrombophlebitis of the leg
Treatment for superficial thrombophlebitis of the leg
Use of fibrinogen concentrate in patients with bleeding 
Use of fibrinogen concentrate in patients with bleeding 
Vasopressors for hypotensive shock
Vasopressors for hypotensive shock
Vena caval filters for the prevention of pulmonary embolism
Vena caval filters for the prevention of pulmonary embolism
VASCULAR DISEASES PERIPHERAL AND CENTRAL ACCESS - SHOCK (17)
Central venous access sites to prevent venous blood clots, blood vessel narrowing, and infection
Central venous access sites to prevent venous blood clots, blood vessel narrowing, and infection
Controlled hypotension versus normotensive resuscitation strategy for people with ruptured abdominal aortic aneurysm
Controlled hypotension versus normotensive resuscitation strategy for people with ruptured abdominal aortic aneurysm
Do blood thinners prevent blood clots in children who are treated using central lines?
Do blood thinners prevent blood clots in children who are treated using central lines?
Drug treatment for small abdominal aortic aneurysms
Drug treatment for small abdominal aortic aneurysms
Drugs to break down blood clots for people with sudden onset peripheral arterial occlusion
Drugs to break down blood clots for people with sudden onset peripheral arterial occlusion
Heparin versus normal saline locking for prevention of occlusion in central venous catheters in adults
Heparin versus normal saline locking for prevention of occlusion in central venous catheters in adults
Intravenous naftidrofuryl for treating critical limb ischaemia
Intravenous naftidrofuryl for treating critical limb ischaemia
Surgery versus thrombolysis for the initial management of acute limb ischaemia
Surgery versus thrombolysis for the initial management of acute limb ischaemia
Treatment for superficial thrombophlebitis of the leg
GYNECOLOGY - PREGNANCY AND CHILD BIRTH (102)
Anaesthesia or analgesia during the manual removal of a retained placenta
Anaesthesia or analgesia during the manual removal of a retained placenta
Anti-D administration after spontaneous miscarriage for preventing Rhesus alloimmunisation
Anti-D administration after spontaneous miscarriage for preventing Rhesus alloimmunisation
Antibiotics for mastitis in breastfeeding women
Antibiotics for mastitis in breastfeeding women
Antibiotics for rupture of membranes when a pregnant women is at or near term but not in labour
Antibiotics for rupture of membranes when a pregnant women is at or near term but not in labour
Antibiotics for treating bacterial vaginosis in pregnancy
Antibiotics for treating bacterial vaginosis in pregnancy
Antifibrinolytic drugs to treat heavy bleeding after childbirth
Antifibrinolytic drugs to treat heavy bleeding after childbirth
Antifibrinolytics (such as tranexamic acid) for treatment of heavy menstrual bleeding
Antifibrinolytics (such as tranexamic acid) for treatment of heavy menstrual bleeding
Antiplatelet agents for preventing pre-eclampsia and its complications
Antiplatelet agents for preventing pre-eclampsia and its complications
Antispasmodics for labour
Antispasmodics for labour
Are non-steroidal anti-inflammatory drugs safe and effective for treating heavy menstrual bleeding?
Are non-steroidal anti-inflammatory drugs safe and effective for treating heavy menstrual bleeding?
Calcium channel blockers for inhibiting preterm labour and birth
Calcium channel blockers for inhibiting preterm labour and birth
Carbetocin for preventing postpartum haemorrhage
Carbetocin for preventing postpartum haemorrhage
Cervical assessment by ultrasound for preventing preterm delivery
Cervical assessment by ultrasound for preventing preterm delivery
Combinations of tocolytic drugs for inhibiting preterm labour
Combinations of tocolytic drugs for inhibiting preterm labour
Duration of treatment for asymptomatic bacteriuria during pregnancy
Duration of treatment for asymptomatic bacteriuria during pregnancy
Early skin-to-skin contact for mothers and their healthy newborn infants
Early skin-to-skin contact for mothers and their healthy newborn infants
Inhaled analgesia for relieving pain during labour
Inhaled analgesia for relieving pain during labour
Interventions for nausea and vomiting in early pregnancy
Interventions for nausea and vomiting in early pregnancy
Interventions for treating severe nausea and vomiting during pregnancy (hyperemesis gravidarum)
Interventions for treating severe nausea and vomiting during pregnancy (hyperemesis gravidarum)
Intravenous fluids for preventing prolonged labour in women giving birth to their first baby
Intravenous fluids for preventing prolonged labour in women giving birth to their first baby
Is it safer to deliver a baby immediately or wait if the mother has high blood pressure after 34 weeks of pregnancy that is not persistently severe?
Is it safer to deliver a baby immediately or wait if the mother has high blood pressure after 34 weeks of pregnancy that is not persistently severe?
Management of intussusception in children
Management of intussusception in children
Mechanical and surgical interventions for treating women with severe bleeding after childbirth
Mechanical and surgical interventions for treating women with severe bleeding after childbirth
Medical therapies for treating heavy menstrual bleeding in women with bleeding disorders
Medical therapies for treating heavy menstrual bleeding in women with bleeding disorders
Medications for reducing contractions during labour for excessively strong/frequent contractions or where the unborn baby is thought to be distressed
Medications for reducing contractions during labour for excessively strong/frequent contractions or where the unborn baby is thought to be distressed
Methods of emergency contraception
Methods of emergency contraception
Newborn resuscitation training programmes for improving the health and survival of newborns
Newborn resuscitation training programmes for improving the health and survival of newborns
Non-opioid drugs for managing pain in labour
Non-opioid drugs for managing pain in labour
Nonsteroidal anti-inflammatory drugs for dysmenorrhoea
Nonsteroidal anti-inflammatory drugs for dysmenorrhoea
Nonsteroidal anti-inflammatory drugs for management of pain in women with endometriosis
Nonsteroidal anti-inflammatory drugs for management of pain in women with endometriosis
Oxytocin for preventing postpartum haemorrhage in non-facility birth settings
Oxytocin for preventing postpartum haemorrhage in non-facility birth settings
Oxytocin injected into a vein or muscle for reducing blood loss after vaginal birth
Oxytocin injected into a vein or muscle for reducing blood loss after vaginal birth
Oxytocin receptor antagonists for inhibiting preterm labour
Oxytocin receptor antagonists for inhibiting preterm labour
Paracetamol (acetaminophen) for prevention or treatment of pain in newborns
Paracetamol (acetaminophen) for prevention or treatment of pain in newborns
Paracetamol for relief of perineal pain after birth
Paracetamol for relief of perineal pain after birth
Repeated use of hormonal drugs right before or after sex to prevent pregnancy
Repeated use of hormonal drugs right before or after sex to prevent pregnancy
Scanning imaging techniques for the exclusion of pulmonary embolism during pregnancy
Scanning imaging techniques for the exclusion of pulmonary embolism during pregnancy
Selective versus routine use of episiotomy for vaginal birth
Selective versus routine use of episiotomy for vaginal birth
Specialist teams for neonatal transport to neonatal intensive care units for prevention of morbidity and mortality
Specialist teams for neonatal transport to neonatal intensive care units for prevention of morbidity and mortality
Terbutaline pump maintenance therapy after threatened preterm labour for reducing adverse neonatal outcomes
Terbutaline pump maintenance therapy after threatened preterm labour for reducing adverse neonatal outcomes
The effectiveness of blood testing in the management of pyelonephritis in pregnancy for improving outcomes
The effectiveness of blood testing in the management of pyelonephritis in pregnancy for improving outcomes
The risk of heart attack and stroke in women using birth control pills
The risk of heart attack and stroke in women using birth control pills
The use of respiratory support without endotracheal tube (i.e. non-invasive) in babies to manage rapid breathing (transient tachypnea of the newborn)
The use of respiratory support without endotracheal tube (i.e. non-invasive) in babies to manage rapid breathing (transient tachypnea of the newborn)
Tocolytics for preterm premature rupture of membranes
Tocolytics for preterm premature rupture of membranes
Tranexamic acid for preventing bleeding after delivery
Tranexamic acid for preventing bleeding after delivery
Treatment for excessive bleeding after childbirth
Treatment for excessive bleeding after childbirth
Treatments for preventing and treating low-back and pelvic pain during pregnancy
Treatments for preventing and treating low-back and pelvic pain during pregnancy
Uterine massage for preventing postpartum haemorrhage
Uterine massage for preventing postpartum haemorrhage
What are the benefits and risks of giving corticosteroids to pregnant women at risk of premature birth?
What are the benefits and risks of giving corticosteroids to pregnant women at risk of premature birth?
Which drug is best for reducing excessive blood loss after birth?
Which drug is best for reducing excessive blood loss after birth?
Which drug is best for treating excessive bleeding after childbirth?
Which drug is best for treating excessive bleeding after childbirth?
INFECTIOUS DISEASES (157)
ANTIBIOTICS (8)
A single beta lactam antibiotic versus a beta lactam-aminoglycoside combination for patients with severe infection
A single beta lactam antibiotic versus a beta lactam-aminoglycoside combination for patients with severe infection
Alternative dosing strategies for intravenous antibiotics to treat severe infections
Alternative dosing strategies for intravenous antibiotics to treat severe infections
Antibiotic treatment for asymptomatic bacteriuria
Antibiotic treatment for asymptomatic bacteriuria
Antibiotics to treat suspected cases meningitis due to infection with meningococcus before confirmation of diagnosis
Antibiotics to treat suspected cases meningitis due to infection with meningococcus before confirmation of diagnosis
COVID-19 (26)
Are digital contact tracing technologies effective during infectious disease outbreaks?
Are digital contact tracing technologies effective during infectious disease outbreaks?
Can international travel-related control measures contain the spread of the COVID-19 pandemic?
Can international travel-related control measures contain the spread of the COVID-19 pandemic?
Can symptoms and medical examination accurately diagnose COVID-19?
Can symptoms and medical examination accurately diagnose COVID-19?
Factors that influence whether healthcare workers follow infection prevention and control guidelines for respiratory infectious diseases
Factors that influence whether healthcare workers follow infection prevention and control guidelines for respiratory infectious diseases
How accurate are rapid tests for diagnosing COVID-19?
How accurate are rapid tests for diagnosing COVID-19?
How accurate are routine laboratory tests for diagnosis of COVID-19?
How accurate are routine laboratory tests for diagnosis of COVID-19?
How accurate is chest imaging for diagnosing COVID-19?
How accurate is chest imaging for diagnosing COVID-19?
How effective is screening for COVID-19?
How effective is screening for COVID-19?
Is chloroquine or hydroxychloroquine useful in treating people with COVID-19, or in preventing infection in people who have been exposed to the virus?
Is chloroquine or hydroxychloroquine useful in treating people with COVID-19, or in preventing infection in people who have been exposed to the virus?
Is plasma from people who have recovered from COVID-19 an effective treatment for people with COVID-19?
Is plasma from people who have recovered from COVID-19 an effective treatment for people with COVID-19?
Protective clothes and equipment for healthcare workers to prevent them catching coronavirus and other highly infectious diseases
Protective clothes and equipment for healthcare workers to prevent them catching coronavirus and other highly infectious diseases
What is the diagnostic accuracy of antibody tests for the detection of infection with the COVID-19 virus?
What is the diagnostic accuracy of antibody tests for the detection of infection with the COVID-19 virus?
What type of heart and blood vessel problems complicate COVID-19 infections, how common are they and what other medical conditions do these patients have?
What type of heart and blood vessel problems complicate COVID-19 infections, how common are they and what other medical conditions do these patients have?
HIV/AIDS (4)
Antiretroviral pre-exposure prophylaxis (PrEP) for preventing HIV in high-risk individuals
Antiretroviral pre-exposure prophylaxis (PrEP) for preventing HIV in high-risk individuals
The use of telephone for the delivery of HIV testing results
The use of telephone for the delivery of HIV testing results
INFECTIOUS DISEASES-OTHER (69)
Adjustment of antimicrobial agents for adults with sepsis, severe sepsis or septic shock
Adjustment of antimicrobial agents for adults with sepsis, severe sepsis or septic shock
Antibiotic therapy for the treatment of methicillin-resistant Staphylococcus aureus (MRSA)-infected or colonised non surgical wounds
Antibiotic therapy for the treatment of methicillin-resistant Staphylococcus aureus (MRSA)-infected or colonised non surgical wounds
Antibiotics for covert bacteriuria in children
Antibiotics for covert bacteriuria in children
Antibiotics for the common cold, an infection of the upper respiratory tract
Antibiotics for the common cold, an infection of the upper respiratory tract
Antibiotics for the treatment of leptospirosis
Antibiotics for the treatment of leptospirosis
Antibiotics for treating human brucellosis
Antibiotics for treating human brucellosis
Antibiotics to treat suspected cases meningitis due to infection with meningococcus before confirmation of diagnosis
Antiepileptic drugs for the primary and secondary prevention of seizures in viral encephalitis
Antiepileptic drugs for the primary and secondary prevention of seizures in viral encephalitis
Antihistamines for the common cold
Antihistamines for the common cold
Automated monitoring for the early detection of sepsis in patients receiving care in intensive care units
Automated monitoring for the early detection of sepsis in patients receiving care in intensive care units
Bathing critically ill patients with chlorhexidine to prevent hospital-acquired infections
Bathing critically ill patients with chlorhexidine to prevent hospital-acquired infections
Corticosteroids for the treatment of parasitic eosinophilic meningitis
Corticosteroids for the treatment of parasitic eosinophilic meningitis
Corticosteroids for treating sepsis
Corticosteroids for treating sepsis
Different fluid therapy strategies for sepsis and septic shock
Different fluid therapy strategies for sepsis and septic shock
Echinacea for preventing and treating the common cold
Echinacea for preventing and treating the common cold
Garlic for the common cold
Garlic for the common cold
Heated, humidified air for the common cold
Heated, humidified air for the common cold
How accurate are nucleic and antigen detection tests in diagnosing leptospirosis?
How accurate are nucleic and antigen detection tests in diagnosing leptospirosis?
Human recombinant activated protein C for severe sepsis and septic shock in adult and paediatric patients
Human recombinant activated protein C for severe sepsis and septic shock in adult and paediatric patients
Intravenous immunoglobulins for treating patients with severe sepsis and septic shock
Intravenous immunoglobulins for treating patients with severe sepsis and septic shock
Intravenous N-acetylcysteine compared to placebo for treatment of systemic inflammatory response syndrome and sepsis in seriously ill adults
Intravenous N-acetylcysteine compared to placebo for treatment of systemic inflammatory response syndrome and sepsis in seriously ill adults
Levels of interleukin-6 in identifying severely ill adult patients with sepsis
Levels of interleukin-6 in identifying severely ill adult patients with sepsis
Non-steroidal anti-inflammatory drugs for the common cold
Non-steroidal anti-inflammatory drugs for the common cold
Oral antihistamine-decongestant-analgesic combinations for the common cold
Oral antihistamine-decongestant-analgesic combinations for the common cold
Procalcitonin evaluation for reducing mortality in adults with sepsis
Procalcitonin evaluation for reducing mortality in adults with sepsis
Rapid diagnostic tests for plague
Rapid diagnostic tests for plague
Smectite for treating children with acute diarrhoea
Smectite for treating children with acute diarrhoea
Steroids for short-term symptom control in infectious mononucleosis (glandular fever)
Steroids for short-term symptom control in infectious mononucleosis (glandular fever)
Steroids for the common cold
Steroids for the common cold
Substituting or adding fluoroquinolones to established first-line antituberculous drug regimens gives no additional benefit or risks
Substituting or adding fluoroquinolones to established first-line antituberculous drug regimens gives no additional benefit or risks
The accuracy of rapid diagnostic tests for detecting typhoid and paratyphoid (enteric) fever
The accuracy of rapid diagnostic tests for detecting typhoid and paratyphoid (enteric) fever
The effect of short duration versus standard duration antibiotic therapy for streptococcal throat infection in children
The effect of short duration versus standard duration antibiotic therapy for streptococcal throat infection in children
Use of corticosteroids for treatment of the newborn with bacterial meningitis
Use of corticosteroids for treatment of the newborn with bacterial meningitis
Vitamin C for preventing and treating tetanus
Vitamin C for preventing and treating tetanus
Vitamin C for preventing and treating the common cold
Vitamin C for preventing and treating the common cold
INFLUENZA (12)
Amantadine and rimantadine to prevent and treat influenza A in children and the elderly
Amantadine and rimantadine to prevent and treat influenza A in children and the elderly
Chinese medicinal herbs for influenza
Chinese medicinal herbs for influenza
Homeopathic Oscillococcinum® for preventing and treating influenza and influenza-like illness
Homeopathic Oscillococcinum® for preventing and treating influenza and influenza-like illness
Neuraminidase inhibitors for preventing and treating influenza in children
Neuraminidase inhibitors for preventing and treating influenza in children
Regulatory information on trials of oseltamivir (Tamiflu) and zanamivir (Relenza) for influenza in adults and children
Regulatory information on trials of oseltamivir (Tamiflu) and zanamivir (Relenza) for influenza in adults and children
Steroids for the treatment of influenza
Steroids for the treatment of influenza
SEXUALLY TRANSMITTED DISEASES (6)
Antiviral medication for the treatment of infectious mononucleosis (glandular fever)
Antiviral medication for the treatment of infectious mononucleosis (glandular fever)
Azithromycin versus penicillin G benzathine for early syphilis
Azithromycin versus penicillin G benzathine for early syphilis
Vaginal inserts for prevention of sexually transmitted infections
Vaginal inserts for prevention of sexually transmitted infections
TROPICAL DISEASES (32)
Administering antimalarial drugs to prevent malaria in infants
Administering antimalarial drugs to prevent malaria in infants
Antibiotics for treating cholera
Antibiotics for treating cholera
Antipyretic measures for treating fever in malaria
Antipyretic measures for treating fever in malaria
Artemether injection for treating people with severe malaria
Artemether injection for treating people with severe malaria
Artemisinin-based combination therapy (ACT) for treating non-severe malaria due to Plasmodium vivax
Artemisinin-based combination therapy (ACT) for treating non-severe malaria due to Plasmodium vivax
Artemisinin-naphthoquine for treating uncomplicated Plasmodium falciparum malaria
Artemisinin-naphthoquine for treating uncomplicated Plasmodium falciparum malaria
Artesunate reduces death from severe malaria
Artesunate reduces death from severe malaria
Can mefloquine prevent malaria during travel to areas where the disease is widespread?
Can mefloquine prevent malaria during travel to areas where the disease is widespread?
Corticosteroids for treating dengue infection in children and adults
Corticosteroids for treating dengue infection in children and adults
Mefloquine for preventing malaria in pregnant women
Mefloquine for preventing malaria in pregnant women
Pyronaridine-artesunate for treating uncomplicated Plasmodium falciparum (P falciparum) malaria
Pyronaridine-artesunate for treating uncomplicated Plasmodium falciparum (P falciparum) malaria
Rapid diagnostic tests for visceral leishmaniasis
Rapid diagnostic tests for visceral leishmaniasis
Rapid diagnostic tests versus clinical diagnosis for managing fever in settings where malaria is common
Rapid diagnostic tests versus clinical diagnosis for managing fever in settings where malaria is common
Rapid tests for diagnosing malaria caused by in people living in areas where malaria is very common
Rapid tests for diagnosing malaria caused by in people living in areas where malaria is very common
Rapid tests for diagnosing malaria caused by Plasmodium vivax or other less common parasites
Rapid tests for diagnosing malaria caused by Plasmodium vivax or other less common parasites
What are the benefits and risks of atovaquone-proguanil for treating uncomplicated malaria caused by the Plasmodium falciparum parasite?
What are the benefits and risks of atovaquone-proguanil for treating uncomplicated malaria caused by the Plasmodium falciparum parasite?
LUNGS AND AIRWAYS (216)
ASTHMA (62)
Addition of intravenous beta2-agonists to inhaled beta2-agonists for acute asthma
Addition of intravenous beta2-agonists to inhaled beta2-agonists for acute asthma
Anti-leukotriene agents compared to inhaled corticosteroids for people with asthma
Anti-leukotriene agents compared to inhaled corticosteroids for people with asthma
Anticholinergic therapy for acute asthma in children
Anticholinergic therapy for acute asthma in children
Are antibiotics a safe and effective additional treatment for asthma exacerbations?
Are antibiotics a safe and effective additional treatment for asthma exacerbations?
Are inhaled anticholinergics added to β2-agonists beneficial in children hospitalised with acute asthma?
Are inhaled anticholinergics added to β2-agonists beneficial in children hospitalised with acute asthma?
Asthma reliever inhalers (beta2-agonists) used for exercise-induced asthma and exercise-induced bronchoconstriction
Asthma reliever inhalers (beta2-agonists) used for exercise-induced asthma and exercise-induced bronchoconstriction
Can exhaled nitric oxide be used to adjust asthma medications in children with asthma?
Can exhaled nitric oxide be used to adjust asthma medications in children with asthma?
Combined beta-agonists and anticholinergics compared to beta-agonists alone for adults with asthma treated in emergency departments
Combined beta-agonists and anticholinergics compared to beta-agonists alone for adults with asthma treated in emergency departments
Different doses and durations of oral steroids for asthma attacks
Different doses and durations of oral steroids for asthma attacks
Do magnesium sulfate infusions reduce the need for hospital admission in adults with acute asthma?
Do magnesium sulfate infusions reduce the need for hospital admission in adults with acute asthma?
Do magnesium sulfate infusions reduce the need for hospital admission in children with acute asthma?
Do magnesium sulfate infusions reduce the need for hospital admission in children with acute asthma?
Does adding antileukotriene agents to usual care when people are suffering an asthma attack in the emergency department help?
Does adding antileukotriene agents to usual care when people are suffering an asthma attack in the emergency department help?
Does an aminophylline injection in addition to bronchodilators for an asthma attack improve lung function and other outcomes or cause harm?
Does an aminophylline injection in addition to bronchodilators for an asthma attack improve lung function and other outcomes or cause harm?
Early use of inhaled corticosteroids in the emergency department treatment of acute asthma
Early use of inhaled corticosteroids in the emergency department treatment of acute asthma
Holding chambers (spacers) versus nebulisers for delivery of beta-agonist relievers in the treatment of an asthma attack
Holding chambers (spacers) versus nebulisers for delivery of beta-agonist relievers in the treatment of an asthma attack
In people with asthma are single inhalers that contain both formoterol and budesonide better than current best practice?
In people with asthma are single inhalers that contain both formoterol and budesonide better than current best practice?
Increasing the dose of inhaled steroids or continuing the usual dose to treat asthma attacks in adults and children
Increasing the dose of inhaled steroids or continuing the usual dose to treat asthma attacks in adults and children
Inhaled corticosteroids for acute asthma following emergency department discharge
Inhaled corticosteroids for acute asthma following emergency department discharge
Interventions for acute severe asthma attacks in children: an overview of Cochrane Reviews
Interventions for acute severe asthma attacks in children: an overview of Cochrane Reviews
Interventions for managing asthma in pregnancy
Interventions for managing asthma in pregnancy
Intramuscular versus oral corticosteroids for acute asthma
Intramuscular versus oral corticosteroids for acute asthma
Intravenous beta2-agonists and intravenous aminophylline for acute asthma
Intravenous beta2-agonists and intravenous aminophylline for acute asthma
Is inhaled magnesium sulfate a safe and effective treatment for people with asthma attacks?
Is inhaled magnesium sulfate a safe and effective treatment for people with asthma attacks?
Is taking inhaled corticosteroids only when asthma symptoms get worse as safe and effective as taking inhaled corticosteroids every day?
Is taking inhaled corticosteroids only when asthma symptoms get worse as safe and effective as taking inhaled corticosteroids every day?
Non-invasive positive pressure ventilation for treatment of respiratory failure due to severe acute exacerbations of asthma
Non-invasive positive pressure ventilation for treatment of respiratory failure due to severe acute exacerbations of asthma
Oral corticosteroid treatment started by patients or parents during a severe asthma attack
Oral corticosteroid treatment started by patients or parents during a severe asthma attack
Regular treatment with formoterol and inhaled steroids for chronic asthma: serious adverse events
Regular treatment with formoterol and inhaled steroids for chronic asthma: serious adverse events
Role of ketamine for management of acute severe asthma in children
Role of ketamine for management of acute severe asthma in children
Sublingual immunotherapy for asthma
Sublingual immunotherapy for asthma
Vaccines for preventing flu in people with asthma
Vaccines for preventing flu in people with asthma
Vitamins C and E for asthma and exercise-induced breathlessness
Vitamins C and E for asthma and exercise-induced breathlessness
COPD (34)
Airway clearance techniques for chronic obstructive pulmonary disease
Airway clearance techniques for chronic obstructive pulmonary disease
Are antibiotics beneficial for flare-ups of chronic obstructive pulmonary disease?
Are antibiotics beneficial for flare-ups of chronic obstructive pulmonary disease?
Are shorter courses of systemic steroids as effective as conventional longer courses in the treatment of patients with flare-ups of COPD?
Are shorter courses of systemic steroids as effective as conventional longer courses in the treatment of patients with flare-ups of COPD?
Are tiotropium plus combination inhalers better than tiotropium or combination inhalers alone for the treatment of COPD?
Are tiotropium plus combination inhalers better than tiotropium or combination inhalers alone for the treatment of COPD?
Combined inhalers compared to tiotropium inhalers for the treatment of chronic obstructive pulmonary disease
Combined inhalers compared to tiotropium inhalers for the treatment of chronic obstructive pulmonary disease
Combined inhalers versus placebo for the treatment of chronic obstructive pulmonary disease (COPD)
Combined inhalers versus placebo for the treatment of chronic obstructive pulmonary disease (COPD)
Do people recover from exacerbations of chronic obstructive pulmonary disease (COPD) better in their own home than in the hospital emergency room?
Do people recover from exacerbations of chronic obstructive pulmonary disease (COPD) better in their own home than in the hospital emergency room?
Do systemic corticosteroids improve treatment outcomes in flare-ups of chronic obstructive pulmonary disease?
Do systemic corticosteroids improve treatment outcomes in flare-ups of chronic obstructive pulmonary disease?
In stable COPD, should inhaled corticosteroids be used with combination long-acting beta-agonist/long-acting muscarinic antagonist inhalers?
In stable COPD, should inhaled corticosteroids be used with combination long-acting beta-agonist/long-acting muscarinic antagonist inhalers?
Inhaled steroids for stable chronic obstructive pulmonary disease
Inhaled steroids for stable chronic obstructive pulmonary disease
Long-acting beta2-agonists for people with COPD
Long-acting beta2-agonists for people with COPD
Mucolytic agents for chronic bronchitis or chronic obstructive pulmonary disease
Mucolytic agents for chronic bronchitis or chronic obstructive pulmonary disease
Non-invasive ventilation for people with respiratory failure due to exacerbation of chronic obstructive pulmonary disease (COPD)
Non-invasive ventilation for people with respiratory failure due to exacerbation of chronic obstructive pulmonary disease (COPD)
Oxygen therapy in the pre-hospital setting for sudden worsening of chronic obstructive pulmonary disease
Oxygen therapy in the pre-hospital setting for sudden worsening of chronic obstructive pulmonary disease
Prophylactic antibiotics for people with COPD
Prophylactic antibiotics for people with COPD
Tiotropium for managing COPD
Tiotropium for managing COPD
Tiotropium versus ipratropium bromide in the management of COPD
Tiotropium versus ipratropium bromide in the management of COPD
LUNGS AND AIRWAYS-OTHER (120)
A gentler form of mechanical breathing for people affected by severe lung failure
A gentler form of mechanical breathing for people affected by severe lung failure
Acetylcysteine and carbocysteine to treat acute upper and lower respiratory tract infections in children without chronic broncho-pulmonary disease
Acetylcysteine and carbocysteine to treat acute upper and lower respiratory tract infections in children without chronic broncho-pulmonary disease
Airway clearance techniques in bronchiectasis
Airway clearance techniques in bronchiectasis
Antibiotic treatment for people with acute bronchitis
Antibiotic treatment for people with acute bronchitis
Antibiotic treatment for Stenotrophomonas maltophilia in people with cystic fibrosis
Antibiotic treatment for Stenotrophomonas maltophilia in people with cystic fibrosis
Antibiotics for bronchiolitis in children under two years of age
Antibiotics for bronchiolitis in children under two years of age
Antibiotics for common respiratory infections with unclear causes and undifferentiated symptoms in children up to five years of age
Antibiotics for common respiratory infections with unclear causes and undifferentiated symptoms in children up to five years of age
Antibiotics for community-acquired pneumonia in adolescent and adult outpatients
Antibiotics for community-acquired pneumonia in adolescent and adult outpatients
Antibiotics for persistent cough or wheeze following acute bronchiolitis in children
Antibiotics for persistent cough or wheeze following acute bronchiolitis in children
Antibiotics to treat respiratory infections caused by the bacteria Mycoplasma pneumoniae in children
Antibiotics to treat respiratory infections caused by the bacteria Mycoplasma pneumoniae in children
Anticoagulant treatment for subsegmental pulmonary embolism
Anticoagulant treatment for subsegmental pulmonary embolism
Antifibrinolytic therapy to reduce haemoptysis
Antifibrinolytic therapy to reduce haemoptysis
Approaches to guiding oxygen therapy in adult intensive care patients with acute respiratory distress syndrome
Approaches to guiding oxygen therapy in adult intensive care patients with acute respiratory distress syndrome
Azithromycin for acute lower respiratory tract infections
Azithromycin for acute lower respiratory tract infections
Beta2-agonist drugs for treating cough or a clinical diagnosis of acute bronchitis
Beta2-agonist drugs for treating cough or a clinical diagnosis of acute bronchitis
Bronchodilators for bronchiolitis for infants with first-time wheezing
Bronchodilators for bronchiolitis for infants with first-time wheezing
Chest physiotherapy for acute bronchiolitis in children younger than two years of age
Chest physiotherapy for acute bronchiolitis in children younger than two years of age
Chest physiotherapy for pneumonia in adults
Chest physiotherapy for pneumonia in adults
Chest X-rays in acute chest infections
Chest X-rays in acute chest infections
Chinese herbs combined with Western medicine for treating severe acute respiratory syndrome (SARS)
Chinese herbs combined with Western medicine for treating severe acute respiratory syndrome (SARS)
Clinical symptoms and signs for the diagnosis of Mycoplasma pneumoniae in children and adolescents with community-acquired pneumonia
Clinical symptoms and signs for the diagnosis of Mycoplasma pneumoniae in children and adolescents with community-acquired pneumonia
Comparing treatment of non-severe pneumonia, in children aged 2 to 59 months, with and without antibiotics
Comparing treatment of non-severe pneumonia, in children aged 2 to 59 months, with and without antibiotics
Continuous negative extrathoracic pressure or continuous positive airway pressure for children with acute respiratory failure and shortage of oxygen
Continuous negative extrathoracic pressure or continuous positive airway pressure for children with acute respiratory failure and shortage of oxygen
Continuous positive airway pressure (CPAP) for acute bronchiolitis in children
Continuous positive airway pressure (CPAP) for acute bronchiolitis in children
Delayed antibiotic prescriptions for respiratory tract infections
Delayed antibiotic prescriptions for respiratory tract infections
Different antibiotics for community-acquired pneumonia in otherwise healthy children younger than 18 years of age in hospital and outpatient settings
Different antibiotics for community-acquired pneumonia in otherwise healthy children younger than 18 years of age in hospital and outpatient settings
Drugs to treat acute respiratory distress syndrome in adults
Drugs to treat acute respiratory distress syndrome in adults
Elective (regular) versus symptomatic intravenous antibiotic therapy for cystic fibrosis
Elective (regular) versus symptomatic intravenous antibiotic therapy for cystic fibrosis
Embolisation therapy for pulmonary arteriovenous malformations
Embolisation therapy for pulmonary arteriovenous malformations
Glucocorticoids for acute viral bronchiolitis in infants and young children under two years of age
Glucocorticoids for acute viral bronchiolitis in infants and young children under two years of age
Heliox inhalation therapy for bronchiolitis in infants
Heliox inhalation therapy for bronchiolitis in infants
High-frequency oscillation for the treatment of acute respiratory distress syndrome (ARDS)
High-frequency oscillation for the treatment of acute respiratory distress syndrome (ARDS)
Honey for acute cough in children
Honey for acute cough in children
How accurate is chest ultrasonography compared to supine chest radiography for diagnosis of traumatic pneumothorax in the emergency department?
How accurate is chest ultrasonography compared to supine chest radiography for diagnosis of traumatic pneumothorax in the emergency department?
Inhaled corticosteroids for subacute cough in children
Inhaled corticosteroids for subacute cough in children
Interventions for the management of fluid around the lungs (pleural fluid) caused by cancer
Interventions for the management of fluid around the lungs (pleural fluid) caused by cancer
Is hypertonic saline solution via nebuliser effective and safe for infants with acute bronchiolitis?
Is hypertonic saline solution via nebuliser effective and safe for infants with acute bronchiolitis?
Is treatment with corticosteroids beneficial and safe for people with pneumonia?
Is treatment with corticosteroids beneficial and safe for people with pneumonia?
Is vitamin D an effective and safe addition to antibiotics to treat children with acute pneumonia?
Is vitamin D an effective and safe addition to antibiotics to treat children with acute pneumonia?
Leukotriene inhibitors for bronchiolitis in infants and young children
Leukotriene inhibitors for bronchiolitis in infants and young children
Low blood oxygen levels versus normal blood oxygen levels in ventilated severely ill people
Low blood oxygen levels versus normal blood oxygen levels in ventilated severely ill people
Observation alone versus drain tube or needle insertion (interventional) for primary spontaneous pneumothorax in adults without previous lung disease.
Observation alone versus drain tube or needle insertion (interventional) for primary spontaneous pneumothorax in adults without previous lung disease.
Over-the-counter medications to help reduce cough for children and adults on antibiotics for acute pneumonia
Over-the-counter medications to help reduce cough for children and adults on antibiotics for acute pneumonia
Oxygen therapy as part of the treatment for respiratory infections in children
Oxygen therapy as part of the treatment for respiratory infections in children
Partial liquid ventilation for mechanical ventilation of severely ill children with acute lung injury and acute respiratory distress syndrome
Partial liquid ventilation for mechanical ventilation of severely ill children with acute lung injury and acute respiratory distress syndrome
Positioning for acute respiratory distress in hospitalised infants and children
Positioning for acute respiratory distress in hospitalised infants and children
Positive airway pressure for heart failure associated with central sleep apnoea
Positive airway pressure for heart failure associated with central sleep apnoea
Probiotics for preventing ventilator-associated pneumonia
Probiotics for preventing ventilator-associated pneumonia
Prone (face-down) position for mechanical ventilation of adults with acute respiratory failure
Prone (face-down) position for mechanical ventilation of adults with acute respiratory failure
Rapid viral testing for children in the Emergency Department with fever and respiratory symptoms
Rapid viral testing for children in the Emergency Department with fever and respiratory symptoms
Recruitment manoeuvres as a ventilation strategy for adults with acute respiratory failure due to lung injury
Recruitment manoeuvres as a ventilation strategy for adults with acute respiratory failure due to lung injury
Short-course versus long-course antibiotic treatment for hospital-acquired pneumonia in adult intensive care patients
Short-course versus long-course antibiotic treatment for hospital-acquired pneumonia in adult intensive care patients
Simple aspiration versus intercostal tube drainage for primary spontaneous pneumothorax in adults
Simple aspiration versus intercostal tube drainage for primary spontaneous pneumothorax in adults
Supplemental oxygen for adults admitted to the intensive care unit
Supplemental oxygen for adults admitted to the intensive care unit
Testing blood procalcitonin levels to decide when to start and stop antibiotics in adults with acute respiratory tract infections
Testing blood procalcitonin levels to decide when to start and stop antibiotics in adults with acute respiratory tract infections
The effectiveness of oxygen for adult patients with pneumonia
The effectiveness of oxygen for adult patients with pneumonia
Treatment of the cough in whooping cough
Treatment of the cough in whooping cough
Use of inhaled nitric oxide in patients with acute respiratory failure with low blood oxygen does not improve survival
Use of inhaled nitric oxide in patients with acute respiratory failure with low blood oxygen does not improve survival
Use of rapid point-of-care testing for infection to guide doctors prescribing antibiotics for acute respiratory infections in primary care settings
Use of rapid point-of-care testing for infection to guide doctors prescribing antibiotics for acute respiratory infections in primary care settings
Vitamin C for preventing and treating pneumonia
Vitamin C for preventing and treating pneumonia
MENTAL HEALTH (52)
DEPRESSION - ANXIETY (4)
Drugs to help reduce anxiety in people nearing the end of life due to illness
Drugs to help reduce anxiety in people nearing the end of life due to illness
Medication for treating anxiety disorders in people with alcohol use problems
Medication for treating anxiety disorders in people with alcohol use problems
MENTAL HEALTH-OTHER (42)
Antidepressants for agitation and psychosis in dementia
Antidepressants for agitation and psychosis in dementia
Antipsychotic drugs for elderly people with late-onset schizophrenia
Antipsychotic drugs for elderly people with late-onset schizophrenia
Aripiprazole alone or in combination with other drugs for treating the acute mania phase of bipolar disorder
Aripiprazole alone or in combination with other drugs for treating the acute mania phase of bipolar disorder
Benzodiazepines alone or in combination with antipsychotic drugs for acute psychosis
Benzodiazepines alone or in combination with antipsychotic drugs for acute psychosis
Benzodiazepines for panic disorder in adults
Benzodiazepines for panic disorder in adults
Benzodiazepines for schizophrenia
Benzodiazepines for schizophrenia
Cognitive-behavioural treatments for non-cardiac chest pain
Cognitive-behavioural treatments for non-cardiac chest pain
Crisis intervention for people with severe mental illnesses
Crisis intervention for people with severe mental illnesses
Crisis interventions for people with borderline personality disorder
Crisis interventions for people with borderline personality disorder
Haloperidol as a means of calming people who are aggressive or agitated due to psychosis
Haloperidol as a means of calming people who are aggressive or agitated due to psychosis
Haloperidol dose for the acute phase of schizophrenia
Haloperidol dose for the acute phase of schizophrenia
How effective is aripiprazole for calming people who are aggressive or agitated due to psychosis?
How effective is aripiprazole for calming people who are aggressive or agitated due to psychosis?
Intervention to prevent delirium for critically ill patients in the intensive care unit (ICU)
Intervention to prevent delirium for critically ill patients in the intensive care unit (ICU)
Medicines to treat delirium in critically ill adult patients
Medicines to treat delirium in critically ill adult patients
Melatonin to improve sleep in the intensive care unit
Melatonin to improve sleep in the intensive care unit
Opioids for agitation in dementia
Opioids for agitation in dementia
Risperidone as a means of calming people who are aggressive or agitated due to psychosis
Risperidone as a means of calming people who are aggressive or agitated due to psychosis
The use of benzodiazepines to treat adults with delirium, excluding patients being cared for in intensive care units (ICU)
The use of benzodiazepines to treat adults with delirium, excluding patients being cared for in intensive care units (ICU)
Treatment of epilepsy for people with Alzheimer's disease
Treatment of epilepsy for people with Alzheimer's disease
Treatments for delusional disorder
Treatments for delusional disorder
Valproate preparations for the treatment of agitated behaviour in people with dementia
Valproate preparations for the treatment of agitated behaviour in people with dementia
POST-TRAUMATIC STRESS DISORDER (6)
Multiple session early psychological interventions for prevention of post-traumatic stress disorder
Multiple session early psychological interventions for prevention of post-traumatic stress disorder
Present-centered therapy (PCT) for post-traumatic stress disorder (PTSD) in adults
Present-centered therapy (PCT) for post-traumatic stress disorder (PTSD) in adults
Psychological therapies for the treatment of post-traumatic stress disorder in children and adolescents
Psychological therapies for the treatment of post-traumatic stress disorder in children and adolescents
NEUROLOGY (178)
EPILEPSY (26)
Anticonvulsant therapy for status epilepticus
Anticonvulsant therapy for status epilepticus
Antiepileptic drugs versus no treatment or placebo for children with benign epilepsy with centro temporal spikes
Antiepileptic drugs versus no treatment or placebo for children with benign epilepsy with centro temporal spikes
Calcium antagonists as an add-on therapy for drug-resistant epilepsy
Calcium antagonists as an add-on therapy for drug-resistant epilepsy
Clonazepam add-on therapy for drug-resistant epilepsy in adults and children
Clonazepam add-on therapy for drug-resistant epilepsy in adults and children
Drug management for acute tonic-clonic convulsions (fits), including convulsive status epilepticus in children
Drug management for acute tonic-clonic convulsions (fits), including convulsive status epilepticus in children
Immediate antiepileptic drug treatment, versus placebo, deferred, or no treatment for first unprovoked seizure
Immediate antiepileptic drug treatment, versus placebo, deferred, or no treatment for first unprovoked seizure
Ketogenic diets for drug-resistant epilepsy
Ketogenic diets for drug-resistant epilepsy
Lamotrigine add-on therapy for drug-resistant focal epilepsy
Lamotrigine add-on therapy for drug-resistant focal epilepsy
Lamotrigine as add-on therapy for drug-resistant generalised tonic-clonic seizures
Lamotrigine as add-on therapy for drug-resistant generalised tonic-clonic seizures
Phenobarbitone versus phenytoin monotherapy (single-drug treatment) for epilepsy
Phenobarbitone versus phenytoin monotherapy (single-drug treatment) for epilepsy
Prophylactic drug management for febrile seizures in children
Prophylactic drug management for febrile seizures in children
Propofol versus thiopental sodium for the treatment of refractory status epilepticus (RSE)
Propofol versus thiopental sodium for the treatment of refractory status epilepticus (RSE)
Treatments to prevent Sudden Unexpected Death in Epilepsy (SUDEP)
Treatments to prevent Sudden Unexpected Death in Epilepsy (SUDEP)
MIGRAINE (24)
Aspirin with or without an antiemetic for acute migraine headaches in adults
Aspirin with or without an antiemetic for acute migraine headaches in adults
Diclofenac with or without an antiemetic for acute migraine headaches in adults
Diclofenac with or without an antiemetic for acute migraine headaches in adults
Drugs for the acute treatment of migraine in children and adolescents
Drugs for the acute treatment of migraine in children and adolescents
Ibuprofen with or without an antiemetic for acute migraine headaches in adults
Ibuprofen with or without an antiemetic for acute migraine headaches in adults
Naproxen for acute migraine in adults
Naproxen for acute migraine in adults
Normal pressure oxygen therapy and hyperbaric oxygen therapy for migraine and cluster headaches
Normal pressure oxygen therapy and hyperbaric oxygen therapy for migraine and cluster headaches
Oral aspirin for treatment of acute episodic tension-type headache in adults
Oral aspirin for treatment of acute episodic tension-type headache in adults
Paracetamol (acetaminophen) with or without an antiemetic for acute migraine in adults
Paracetamol (acetaminophen) with or without an antiemetic for acute migraine in adults
Sumatriptan (oral route of administration) for acute migraine attacks in adults
Sumatriptan (oral route of administration) for acute migraine attacks in adults
Sumatriptan (subcutaneous route of administration) for acute migraine attacks in adults
Sumatriptan (subcutaneous route of administration) for acute migraine attacks in adults
Sumatriptan plus naproxen for acute migraine attacks in adults
Sumatriptan plus naproxen for acute migraine attacks in adults
Zolmitriptan for acute migraine attacks in adults
Zolmitriptan for acute migraine attacks in adults
NEUROLOGY-OTHER (56)
Antibiotics for preventing meningococcal infections
Antibiotics for preventing meningococcal infections
Aspirin, steroid and non-steroidal anti-inflammatory drugs use for treating Alzheimer's disease
Aspirin, steroid and non-steroidal anti-inflammatory drugs use for treating Alzheimer's disease
Baseline scores of Mini-Mental State examination (MMSE) for early prediction of developing dementia in people with mild cognitive impairments (MCI)
Baseline scores of Mini-Mental State examination (MMSE) for early prediction of developing dementia in people with mild cognitive impairments (MCI)
Betahistine for symptoms of vertigo
Betahistine for symptoms of vertigo
Corticosteroids for bacterial meningitis
Corticosteroids for bacterial meningitis
Dopamine agents for hepatic encephalopathy
Dopamine agents for hepatic encephalopathy
Drug treatment for pain in Guillain-Barré syndrome
Drug treatment for pain in Guillain-Barré syndrome
Drug treatment other than corticosteroids, intravenous immunoglobulin and plasma exchange for acute Guillain Barré syndrome
Drug treatment other than corticosteroids, intravenous immunoglobulin and plasma exchange for acute Guillain Barré syndrome
Drugs for preventing headache after a lumbar puncture
Drugs for preventing headache after a lumbar puncture
Drugs for treating headache after a lumbar puncture
Drugs for treating headache after a lumbar puncture
Endothelin receptor antagonists for subarachnoid hemorrhage
Endothelin receptor antagonists for subarachnoid hemorrhage
Fluids for people with acute bacterial meningitis
Fluids for people with acute bacterial meningitis
Gabapentin for chronic neuropathic pain in adults
Gabapentin for chronic neuropathic pain in adults
High pressure (hyperbaric) oxygen therapy for Bell's palsy
High pressure (hyperbaric) oxygen therapy for Bell's palsy
Interventions to prevent delirium in hospitalised patients, not including those on intensive care units
Interventions to prevent delirium in hospitalised patients, not including those on intensive care units
Intravenous immunoglobulin for myasthenia gravis
Intravenous immunoglobulin for myasthenia gravis
Jolt accentuation of headache as a test for acute meningitis in emergency settings
Jolt accentuation of headache as a test for acute meningitis in emergency settings
Medical and surgical treatment for ocular myasthenia
Medical and surgical treatment for ocular myasthenia
Oral ibuprofen for acute treatment of episodic tension-type headache in adults
Oral ibuprofen for acute treatment of episodic tension-type headache in adults
Oral ketoprofen for treatment of acute episodic tension-type headache in adults
Oral ketoprofen for treatment of acute episodic tension-type headache in adults
Oral paracetamol for treatment of acute episodic tension-type headache in adults
Oral paracetamol for treatment of acute episodic tension-type headache in adults
Osmotic therapies added to antibiotics for acute bacterial meningitis
Osmotic therapies added to antibiotics for acute bacterial meningitis
Paracetamol (acetaminophen) alone, or in combination with codeine or dihydrocodeine, for neuropathic pain in adults
Paracetamol (acetaminophen) alone, or in combination with codeine or dihydrocodeine, for neuropathic pain in adults
Plasma exchange for chronic inflammatory demyelinating polyradiculoneuropathy
Plasma exchange for chronic inflammatory demyelinating polyradiculoneuropathy
Selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) for preventing tension-type headache
Selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) for preventing tension-type headache
The use of computed tomography angiography (CTA) to confirm the clinical diagnosis of brain death
The use of computed tomography angiography (CTA) to confirm the clinical diagnosis of brain death
Treatments to help blood clotting to improve the recovery of adults with stroke due to bleeding in the brain
Treatments to help blood clotting to improve the recovery of adults with stroke due to bleeding in the brain
Triptans for acute cluster headache
Triptans for acute cluster headache
STROKE AND TRANSIENT ISCHEMIC ATTACK (72)
Accuracy of prehospital stroke scales to identify people with stroke or transient ischemic attack (TIA)
Accuracy of prehospital stroke scales to identify people with stroke or transient ischemic attack (TIA)
Acupuncture for acute stroke
Acupuncture for acute stroke
Antibiotic therapy for preventing infections in people with acute stroke
Antibiotic therapy for preventing infections in people with acute stroke
Anticoagulants for acute ischaemic stroke
Anticoagulants for acute ischaemic stroke
Antiepileptic drugs for the primary and secondary prevention of seizures after subarachnoid haemorrhage
Antiepileptic drugs for the primary and secondary prevention of seizures after subarachnoid haemorrhage
Beta-blockers for preventing stroke recurrence
Beta-blockers for preventing stroke recurrence
Buflomedil for acute ischaemic stroke
Buflomedil for acute ischaemic stroke
Calcium antagonists for acute ischemic stroke
Calcium antagonists for acute ischemic stroke
Cerebrolysin for acute ischaemic stroke
Cerebrolysin for acute ischaemic stroke
Clot-dissolving drugs (different doses, routes of administration and agents) for breaking down a blood clot blocking a blood vessel in the brain
Clot-dissolving drugs (different doses, routes of administration and agents) for breaking down a blood clot blocking a blood vessel in the brain
Clot-dissolving drugs for treating ischaemic stroke in the early stages
Clot-dissolving drugs for treating ischaemic stroke in the early stages
Computed tomography angiography or magnetic resonance angiography for detecting blood vessel abnormalities in patients with intracerebral haemorrhage
Computed tomography angiography or magnetic resonance angiography for detecting blood vessel abnormalities in patients with intracerebral haemorrhage
Continuous or intermittent monitoring of people with acute stroke
Continuous or intermittent monitoring of people with acute stroke
Controlling high blood sugar levels with insulin in people who have had an acute ischaemic stroke
Controlling high blood sugar levels with insulin in people who have had an acute ischaemic stroke
Drug interventions for deliberately altering blood pressure in acute stroke
Drug interventions for deliberately altering blood pressure in acute stroke
Drugs for reducing iron in people with acute stroke
Drugs for reducing iron in people with acute stroke
Early versus delayed mobilisation to prevent further bleeding after spontaneous bleeding on the surface of the brain
Early versus delayed mobilisation to prevent further bleeding after spontaneous bleeding on the surface of the brain
Endovascular therapy versus medical treatment for symptomatic intracranial artery stenosis
Endovascular therapy versus medical treatment for symptomatic intracranial artery stenosis
External counterpulsation for acute ischaemic stroke
External counterpulsation for acute ischaemic stroke
Fibrinogen depleting agents may help to remove blood clots in acute ischaemic stroke
Fibrinogen depleting agents may help to remove blood clots in acute ischaemic stroke
Gamma aminobutyric acid (GABA) receptor agonists for acute stroke
Gamma aminobutyric acid (GABA) receptor agonists for acute stroke
Glycoprotein IIb-IIIa inhibitors for acute ischaemic stroke
Glycoprotein IIb-IIIa inhibitors for acute ischaemic stroke
Haemodilution for acute ischaemic stroke
Haemodilution for acute ischaemic stroke
Hyperbaric oxygen therapy for treating people with acute ischaemic stroke
Hyperbaric oxygen therapy for treating people with acute ischaemic stroke
Mailuoning (a type of traditional Chinese medicine) for improving outcome in people with acute ischaemic stroke
Mailuoning (a type of traditional Chinese medicine) for improving outcome in people with acute ischaemic stroke
Non-pharmacological interventions for preventing secondary vascular events after stroke or transient attack
Non-pharmacological interventions for preventing secondary vascular events after stroke or transient attack
Oral antiplatelet therapy for acute ischaemic stroke
Oral antiplatelet therapy for acute ischaemic stroke
Organised inpatient (stroke unit) care
Organised inpatient (stroke unit) care
Piracetam for acute ischaemic stroke
Piracetam for acute ischaemic stroke
Surgical decompression for cerebral oedema in acute ischaemic stroke
Surgical decompression for cerebral oedema in acute ischaemic stroke
Swallowing therapy for difficulties with swallowing in stroke survivors who have had a recent stroke
Swallowing therapy for difficulties with swallowing in stroke survivors who have had a recent stroke
Transcranial colour Doppler (TCD) and transcranial colour-coded duplex (TCCD), in patients with acute ischaemic stroke for detecting intracranial vessel occlusion or stenosis
Transcranial colour Doppler (TCD) and transcranial colour-coded duplex (TCCD), in patients with acute ischaemic stroke for detecting intracranial vessel occlusion or stenosis
Treatments through the artery versus clot-dissolving drugs for the early treatment of stroke
Treatments through the artery versus clot-dissolving drugs for the early treatment of stroke
Ultrasound (high-frequency sound waves) plus a clot-busting drug for  breaking down a blood clot blocking a blood vessel in the brain
Ultrasound (high-frequency sound waves) plus a clot-busting drug for  breaking down a blood clot blocking a blood vessel in the brain
Use of multiple versus fewer antiplatelet drugs for preventing early recurrence after stroke or transient ischaemic attack
Use of multiple versus fewer antiplatelet drugs for preventing early recurrence after stroke or transient ischaemic attack
Which types of blood-thinning drugs (anticoagulants) are best to prevent blood clots in people soon after stroke?
Which types of blood-thinning drugs (anticoagulants) are best to prevent blood clots in people soon after stroke?
OPHTALMOLOGY (14)
Antibiotics versus placebo for acute bacterial conjunctivitis
Antibiotics versus placebo for acute bacterial conjunctivitis
Corticosteroid eye drops used in addition to standard antibiotic therapy in the treatment of bacterial keratitis
Corticosteroid eye drops used in addition to standard antibiotic therapy in the treatment of bacterial keratitis
Interventions for an acute internal hordeolum
Interventions for an acute internal hordeolum
Medical interventions for traumatic hyphema
Medical interventions for traumatic hyphema
Steroids in the treatment of traumatic optic neuropathy
Steroids in the treatment of traumatic optic neuropathy
Topical non-steroidal anti-inflammatory drugs (NSAIDs) for the treatment of pain in traumatic corneal abrasions
Topical non-steroidal anti-inflammatory drugs (NSAIDs) for the treatment of pain in traumatic corneal abrasions
Valacyclovir compared with acyclovir for the treatment of herpes zoster ophthalmicus in people with an otherwise normal immune system
Valacyclovir compared with acyclovir for the treatment of herpes zoster ophthalmicus in people with an otherwise normal immune system
PEDIATRICS (18)
Alternating and combined antipyretics for treatment of fever in children
Alternating and combined antipyretics for treatment of fever in children
Best position for newborns who need assisted ventilation
Best position for newborns who need assisted ventilation
Beta-blockers for children with congestive heart failure
Beta-blockers for children with congestive heart failure
Continuous positive airways pressure for respiratory distress in preterm infants
Continuous positive airways pressure for respiratory distress in preterm infants
Early versus delayed initiation of continuous positive airway pressure (CPAP) for respiratory distress in preterm infants
Early versus delayed initiation of continuous positive airway pressure (CPAP) for respiratory distress in preterm infants
High-flow nasal cannula (tube) therapy for infants with bronchiolitis
High-flow nasal cannula (tube) therapy for infants with bronchiolitis
Nasal continuous positive airways pressure started immediately after birth for preventing illness and death in very preterm infants
Nasal continuous positive airways pressure started immediately after birth for preventing illness and death in very preterm infants
Racecadotril to treat children under five years of age with acute diarrhoea
Racecadotril to treat children under five years of age with acute diarrhoea
The aspiration of pneumothorax in the newborn with a small needle compared to a larger tube placed through the intercostal space
The aspiration of pneumothorax in the newborn with a small needle compared to a larger tube placed through the intercostal space
RHEUMATOLOGY - NON TRAUMATIC OSTEO ARTICULAR PATHOLOGIES - MUSCULOSKELETEL DISORDERS (48)
Anti-inflammatory drugs for acute low back pain
Anti-inflammatory drugs for acute low back pain
Back schools for acute and subacute non-specific low-back pain
Back schools for acute and subacute non-specific low-back pain
Colchicine for treating acute gout attacks
Colchicine for treating acute gout attacks
Cold-water immersion for preventing and treating muscle soreness after exercise
Cold-water immersion for preventing and treating muscle soreness after exercise
Corticosteroids for chronic inflammatory demyelinating polyradiculoneuropathy
Corticosteroids for chronic inflammatory demyelinating polyradiculoneuropathy
Corticosteroids for Guillain-Barré syndrome
Corticosteroids for Guillain-Barré syndrome
Deep transverse friction massage for the treatment of lateral elbow or lateral knee tendinitis
Deep transverse friction massage for the treatment of lateral elbow or lateral knee tendinitis
Diagnostic tests for assessing rotator cuff tears in people with shoulder pain for whom surgery is being considered
Diagnostic tests for assessing rotator cuff tears in people with shoulder pain for whom surgery is being considered
Exercise for Neck Pain
Exercise for Neck Pain
Image-guided versus blind glucocorticoid injection for shoulder pain
Image-guided versus blind glucocorticoid injection for shoulder pain
Interleukin-1 inhibitors for acute gout
Interleukin-1 inhibitors for acute gout
Intravenous immunoglobulin for Guillain-Barré syndrome
Intravenous immunoglobulin for Guillain-Barré syndrome
Manipulation and mobilisation for neck disorders
Manipulation and mobilisation for neck disorders
Muscle energy technique (MET) for non-specific low-back pain
Muscle energy technique (MET) for non-specific low-back pain
Non-steroidal anti-inflammatory drugs (NSAIDs) for acute gout
Non-steroidal anti-inflammatory drugs (NSAIDs) for acute gout
Non-steroidal anti-inflammatory drugs (NSAIDs) for treating tennis elbow pain in adults
Non-steroidal anti-inflammatory drugs (NSAIDs) for treating tennis elbow pain in adults
Non-steroidal anti-inflammatory drugs for low back pain with sciatica
Non-steroidal anti-inflammatory drugs for low back pain with sciatica
Pain in patients with inflammatory arthritis and gastrointestinal or liver problems
Pain in patients with inflammatory arthritis and gastrointestinal or liver problems
Paracetamol for low back pain
Paracetamol for low back pain
Paracetamol for treating people with hip or knee osteoarthritis
Paracetamol for treating people with hip or knee osteoarthritis
Patient education for neck pain
Patient education for neck pain
Physician use of red flags to screen for cancer in patients with new back pain
Physician use of red flags to screen for cancer in patients with new back pain
Physician use of red flags to screen for fractured vertebrae for patients with new back pain
Physician use of red flags to screen for fractured vertebrae for patients with new back pain
Plasma exchange for Guillain-Barré syndrome
Plasma exchange for Guillain-Barré syndrome
SKIN AND ALLERGY (20)
Adrenaline auto-injectors for the treatment of anaphylaxis in the community
Adrenaline auto-injectors for the treatment of anaphylaxis in the community
Antibiotic drugs for treating skin and soft tissue infections
Antibiotic drugs for treating skin and soft tissue infections
Effects of antihistamines on eczema
Effects of antihistamines on eczema
Glucocorticoids for the treatment of anaphylaxis  
Glucocorticoids for the treatment of anaphylaxis  
H1-antihistamines for chronic spontaneous urticaria
H1-antihistamines for chronic spontaneous urticaria
Helminth therapy (worms) for allergic rhinitis
Helminth therapy (worms) for allergic rhinitis
Histamine-blocking drugs for hives
Histamine-blocking drugs for hives
Ivermectin and permethrin for treating scabies
Ivermectin and permethrin for treating scabies
Using oxygen at high pressure (in a compression chamber) for the treatment of individuals with severe soft tissue infection (necrotizing fasciitis)
Using oxygen at high pressure (in a compression chamber) for the treatment of individuals with severe soft tissue infection (necrotizing fasciitis)
What are the benefits and risks of different treatments for bacterial folliculitis and boils (inflammation of the skin around hairs)?
What are the benefits and risks of different treatments for bacterial folliculitis and boils (inflammation of the skin around hairs)?
TECHNICAL PROCEDURES (82)
INTUBATION AND VENTILATION (32)
Comparison of different techniques for planned opening of the trachea
Comparison of different techniques for planned opening of the trachea
Comparison of video-assisted and non-video-assisted devices for intubation of children
Comparison of video-assisted and non-video-assisted devices for intubation of children
Cuffed versus uncuffed tubes in children aged eight years and under, having general anaesthetic
Cuffed versus uncuffed tubes in children aged eight years and under, having general anaesthetic
Do ventilators that manage the reduction of ventilator support (weaning) reduce the duration of weaning compared to strategies managed by clinicians?
Do ventilators that manage the reduction of ventilator support (weaning) reduce the duration of weaning compared to strategies managed by clinicians?
Drugs for preventing major morbidity and mortality related to blood pressure and heart rate changes associated with tracheal intubation
Drugs for preventing major morbidity and mortality related to blood pressure and heart rate changes associated with tracheal intubation
Effect of applying cricoid pressure during rapid sequence induction of general anaesthesia
Effect of applying cricoid pressure during rapid sequence induction of general anaesthesia
Effects of higher versus lower levels of pressure in the lungs at the end of each breath during mechanical ventilation in patients with acute respiratory distress syndrome (ARDS)
Effects of higher versus lower levels of pressure in the lungs at the end of each breath during mechanical ventilation in patients with acute respiratory distress syndrome (ARDS)
High-flow nasal cannulae for breathing support in adult intensive care patients
High-flow nasal cannulae for breathing support in adult intensive care patients
Intubation methods for obese patients requiring general anaesthesia
Intubation methods for obese patients requiring general anaesthesia
Laryngeal mask airway versus bag-mask ventilation or endotracheal intubation for neonatal resuscitation
Laryngeal mask airway versus bag-mask ventilation or endotracheal intubation for neonatal resuscitation
Methods for securing endotracheal tubes in newborn infants
Methods for securing endotracheal tubes in newborn infants
SmartCare™ versus non-automated weaning strategies for weaning time in invasively ventilated critically ill adults
SmartCare™ versus non-automated weaning strategies for weaning time in invasively ventilated critically ill adults
Synchronised mechanical ventilation for respiratory support in newborn infants
Synchronised mechanical ventilation for respiratory support in newborn infants
The use of video devices in assisting the placement of breathing tube in babies
The use of video devices in assisting the placement of breathing tube in babies
Use of noninvasive ventilation (a mask ventilator) holds promise as a method to make it easier to remove adults from conventional ventilators.
Use of noninvasive ventilation (a mask ventilator) holds promise as a method to make it easier to remove adults from conventional ventilators.
Videolaryngoscopes to guide the insertion of breathing tubes in adult surgical patients
Videolaryngoscopes to guide the insertion of breathing tubes in adult surgical patients
TECHNICAL PROCEDURES-OTHER (44)
Anaesthetic drugs for cardioversion
Anaesthetic drugs for cardioversion
Antibiotics at the time of removal of a central line to reduce complications in newborn infants
Antibiotics at the time of removal of a central line to reduce complications in newborn infants
Body position and intake of fluids for preventing headache after a lumbar puncture
Body position and intake of fluids for preventing headache after a lumbar puncture
Central venous catheter coating with antiseptics or antibiotics for reducing catheter-related infections in adults
Central venous catheter coating with antiseptics or antibiotics for reducing catheter-related infections in adults
Comparison of the different ways of giving fluids to patients who cannot drink enough, such as patients with Ebola virus disease
Comparison of the different ways of giving fluids to patients who cannot drink enough, such as patients with Ebola virus disease
Devices with safety features for preventing percutaneous exposure injuries in healthcare staff
Devices with safety features for preventing percutaneous exposure injuries in healthcare staff
Does the speed of injection make a difference in the amount of pain and bruising in people receiving heparin injections?
Does the speed of injection make a difference in the amount of pain and bruising in people receiving heparin injections?
Dressings and securement for central venous catheters (CVCs)
Dressings and securement for central venous catheters (CVCs)
How often should dressings on central venous access devices (CVADs) be changed to reduce catheter-related infection?
How often should dressings on central venous access devices (CVADs) be changed to reduce catheter-related infection?
Hyperbaric oxygen therapy for acute surgical and traumatic wounds
Hyperbaric oxygen therapy for acute surgical and traumatic wounds
Lateral positioning for critically ill adult patients
Lateral positioning for critically ill adult patients
Loop diuretics for patients receiving blood transfusions
Loop diuretics for patients receiving blood transfusions
Needle characteristics that reduce the occurrence of post-dural puncture headache (PDPH)
Needle characteristics that reduce the occurrence of post-dural puncture headache (PDPH)
Plasma transfusion strategies for critically ill patients
Plasma transfusion strategies for critically ill patients
Psychological strategies to reduce pain and distress for children and adolescents getting needles
Psychological strategies to reduce pain and distress for children and adolescents getting needles
Radial artery versus femoral artery approach for performing coronary catheter procedures in people with coronary artery disease
Radial artery versus femoral artery approach for performing coronary catheter procedures in people with coronary artery disease
Replacing a peripheral venous catheter when clinically indicated versus routine replacement
Replacing a peripheral venous catheter when clinically indicated versus routine replacement
Skin antisepsis for reducing central venous catheter-related infections
Skin antisepsis for reducing central venous catheter-related infections
Topical treatment with a blood-clot promoting drug to reduce bleeding
Topical treatment with a blood-clot promoting drug to reduce bleeding
Use of adrenaline with lidocaine for surgery on fingers and toes
Use of adrenaline with lidocaine for surgery on fingers and toes
Use of capnography in emergency department patients being sedated for procedures
Use of capnography in emergency department patients being sedated for procedures
Use of platelet transfusions prior to a lumbar puncture or epidural anaesthetic in people with a low platelet count
Use of platelet transfusions prior to a lumbar puncture or epidural anaesthetic in people with a low platelet count
ULTRASOUND (6)
Ultrasound guidance versus anatomical landmarks for internal jugular vein catheterization
Ultrasound guidance versus anatomical landmarks for internal jugular vein catheterization
Ultrasound guidance versus anatomical landmarks for subclavian or femoral vein catheterization
Ultrasound guidance versus anatomical landmarks for subclavian or femoral vein catheterization
Ultrasound use for insertion of arterial catheters in children
Ultrasound use for insertion of arterial catheters in children
TOBACCO, DRUGS AND ALCOHOL DEPENDENCE - ENVIRONMENTAL EMERGENCIES (22)
ENVIRONMENTAL EMERGENCIES (6)
Electric fans for reducing the health effects of heatwaves
Electric fans for reducing the health effects of heatwaves
Snake antivenoms for treating people who have been bitten by a snake, and have developed abnormal blood clotting
Snake antivenoms for treating people who have been bitten by a snake, and have developed abnormal blood clotting
What are the benefits and risks of treating paraquat poisoning with a combination of steroids and cyclophosphamide (an anti-cancer medicine)?
What are the benefits and risks of treating paraquat poisoning with a combination of steroids and cyclophosphamide (an anti-cancer medicine)?
TOBACCO, DRUGS AND ALCOHOL DEPENDENCE (16)
Alcohol has a biphasic effect on blood pressure and increases heart rate
Alcohol has a biphasic effect on blood pressure and increases heart rate
Baclofen for alcohol withdrawal syndrome
Baclofen for alcohol withdrawal syndrome
Buprenorphine for managing opioid withdrawal
Buprenorphine for managing opioid withdrawal
Effects of perioperative alcohol cessation interventions on postoperative complications following surgery
Effects of perioperative alcohol cessation interventions on postoperative complications following surgery
Interventions for paracetamol (acetaminophen) overdose
Interventions for paracetamol (acetaminophen) overdose
Magnesium for the prevention or treatment of alcohol withdrawal syndrome in adults
Magnesium for the prevention or treatment of alcohol withdrawal syndrome in adults
Motivational interviewing (MI) for preventing alcohol misuse in young adults is not effective enough
Motivational interviewing (MI) for preventing alcohol misuse in young adults is not effective enough
Thiamine for prevention and treatment of Wernicke-Korsakoff syndrome in people who abuse alcohol
Thiamine for prevention and treatment of Wernicke-Korsakoff syndrome in people who abuse alcohol
TRAUMATOLOGY (162)
BLEEDING (10)
Blood-clot promoting drugs for acute traumatic injury
Blood-clot promoting drugs for acute traumatic injury
Platelet transfusions treated to reduce transfusion-transmitted infections for the prevention of bleeding in people with low platelet counts
Platelet transfusions treated to reduce transfusion-transmitted infections for the prevention of bleeding in people with low platelet counts
Recombinant factor VIIa for the prevention and treatment of bleeding in patients without haemophilia
Recombinant factor VIIa for the prevention and treatment of bleeding in patients without haemophilia
TEG and ROTEM for diagnosing trauma‑induced coagulopathy (disorder of the clotting system) in adult trauma patients with bleeding
TEG and ROTEM for diagnosing trauma‑induced coagulopathy (disorder of the clotting system) in adult trauma patients with bleeding
Varying the timing or the volume of intravenous fluids given to people with uncontrolled bleeding due to injury
Varying the timing or the volume of intravenous fluids given to people with uncontrolled bleeding due to injury
BURNS (12)
Antibiotics to prevent burn wounds becoming infected
Antibiotics to prevent burn wounds becoming infected
Antiseptics for Burns
Antiseptics for Burns
Dressings for treating superficial and partial thickness burns
Dressings for treating superficial and partial thickness burns
Interventions for treating phosphorus burns
Interventions for treating phosphorus burns
Lidocaine for pain relief in people with burns
Lidocaine for pain relief in people with burns
Topical treatment for facial burns
Topical treatment for facial burns
FRACTURES (58)
Antibiotics to prevent infection of the brain coverings (meningitis) in patients with basilar skull fracture
Antibiotics to prevent infection of the brain coverings (meningitis) in patients with basilar skull fracture
Aspiration of the elbow joint for treating radial head fractures
Aspiration of the elbow joint for treating radial head fractures
Comparing different types of scan (CT, MRI, bone scan) for diagnosis of clinically suspected scaphoid fractures, when initial radiographs are negative
Comparing different types of scan (CT, MRI, bone scan) for diagnosis of clinically suspected scaphoid fractures, when initial radiographs are negative
Conservative interventions for shaft fractures of the forearm bones in children
Conservative interventions for shaft fractures of the forearm bones in children
Do local anaesthetic nerve blocks provide effective pain relief for adults with a hip fracture?
Do local anaesthetic nerve blocks provide effective pain relief for adults with a hip fracture?
Fixation devices secured across the fracture that are placed either directly or externally for treating hip fractures located outside the hip joint
Fixation devices secured across the fracture that are placed either directly or externally for treating hip fractures located outside the hip joint
Interventions for treating adults with an isolated fracture of the ulnar shaft
Interventions for treating adults with an isolated fracture of the ulnar shaft
Interventions for treating shoulder fractures in adults
Interventions for treating shoulder fractures in adults
Intramedullary nails for extracapsular hip fractures in adults
Intramedullary nails for extracapsular hip fractures in adults
Nerve blocks for initial pain management of thigh bone fractures in children
Nerve blocks for initial pain management of thigh bone fractures in children
Non-surgical interventions for treating a broken collarbone in adolescents and adults
Non-surgical interventions for treating a broken collarbone in adolescents and adults
Optimization of fluid levels in people suffering hip fractures
Optimization of fluid levels in people suffering hip fractures
Pedicle screw fixation methods for traumatic fractures of the thoracic and lumbar spine
Pedicle screw fixation methods for traumatic fractures of the thoracic and lumbar spine
Rehabilitation as part of treatment for adults with a broken wrist
Rehabilitation as part of treatment for adults with a broken wrist
Rehabilitation for ankle fractures in adults
Rehabilitation for ankle fractures in adults
Surgery or non-surgical treatment for broken heel bones
Surgery or non-surgical treatment for broken heel bones
Surgical interventions for treating fractures of the olecranon (an elbow bone) in adults
Surgical interventions for treating fractures of the olecranon (an elbow bone) in adults
Surgical interventions for treating radial head fractures in adults
Surgical interventions for treating radial head fractures in adults
Surgical versus conservative for treatment for acromioclavicular dislocations of the shoulder in adults
Surgical versus conservative for treatment for acromioclavicular dislocations of the shoulder in adults
Surgical versus conservative interventions for treating broken collarbones in adolescents and adults
Surgical versus conservative interventions for treating broken collarbones in adolescents and adults
Surgical versus conservative treatment for ankle fractures in adults
Surgical versus conservative treatment for ankle fractures in adults
Surgical versus non-surgical interventions for treating humeral shaft fractures in adults
Surgical versus non-surgical interventions for treating humeral shaft fractures in adults
Surgical versus non-surgical treatment after kneecap dislocation
Surgical versus non-surgical treatment after kneecap dislocation
Surgical versus non-surgical treatment for thoracolumbar burst fractures without neurological deficit
Surgical versus non-surgical treatment for thoracolumbar burst fractures without neurological deficit
Treatments for breaks in the lower part of the thigh bone in adults
Treatments for breaks in the lower part of the thigh bone in adults
Treatments for broken ankles in children
Treatments for broken ankles in children
Treatments for broken kneecaps in adults
Treatments for broken kneecaps in adults
Ultrasound and shockwave treatment for recently broken bones in adults
Ultrasound and shockwave treatment for recently broken bones in adults
Using oxygen at high pressure (in a compression chamber) for the treatment of broken bones
Using oxygen at high pressure (in a compression chamber) for the treatment of broken bones
HEAD TRAUMA (18)
Acupuncture for acute management and rehabilitation of traumatic brain injury
Acupuncture for acute management and rehabilitation of traumatic brain injury
Barbiturate drugs for people with traumatic brain injury
Barbiturate drugs for people with traumatic brain injury
Concentrated salt solution versus other treatments to lower pressure around the brain for people with acute traumatic brain injury
Concentrated salt solution versus other treatments to lower pressure around the brain for people with acute traumatic brain injury
Does hyperbaric oxygen therapy improve the survival and quality of life in patients with traumatic brain injury?
Does hyperbaric oxygen therapy improve the survival and quality of life in patients with traumatic brain injury?
Elevation of the head during intensive care management in people with severe traumatic brain injury
Elevation of the head during intensive care management in people with severe traumatic brain injury
Hypothermia (body temperature cooling) for people with an injury to the brain
Hypothermia (body temperature cooling) for people with an injury to the brain
Partial removal of skull (decompressive craniectomy) to lower treatment-resistant high pressure in the skull and brain after traumatic brain injury
Partial removal of skull (decompressive craniectomy) to lower treatment-resistant high pressure in the skull and brain after traumatic brain injury
Progesterone for traumatic brain injury
Progesterone for traumatic brain injury
The Lund concept in the treatment of brain injuries
The Lund concept in the treatment of brain injuries
TRAUMATOLOGY-OTHER (50)
Acupuncture for sudden-onset ankle sprains in adults
Acupuncture for sudden-onset ankle sprains in adults
Advanced training in trauma life support for ambulance crews
Advanced training in trauma life support for ambulance crews
Advanced training in trauma life support for hospital staff
Advanced training in trauma life support for hospital staff
Antibiotics for injuries to the abdomen that break through the skin: which antibiotics are effective, and for how long should they be taken?
Antibiotics for injuries to the abdomen that break through the skin: which antibiotics are effective, and for how long should they be taken?
Clinical tests for detecting cervical spine injury (CSI) in children with injuries
Clinical tests for detecting cervical spine injury (CSI) in children with injuries
Different methods of manipulation for reducing pulled elbow in young children
Different methods of manipulation for reducing pulled elbow in young children
How accurate is bedside ultrasound for the diagnosis of injuries to the abdomen or chest in patients with blunt injuries?
How accurate is bedside ultrasound for the diagnosis of injuries to the abdomen or chest in patients with blunt injuries?
Interventions for treating acute elbow dislocations in adults
Interventions for treating acute elbow dislocations in adults
Is surgery or observation better for people who have a severe blunt injury to the liver?
Is surgery or observation better for people who have a severe blunt injury to the liver?
Low molecular weight heparin for prevention of venous thromboembolism in adults with lower-limb immobilization in an outpatient setting
Low molecular weight heparin for prevention of venous thromboembolism in adults with lower-limb immobilization in an outpatient setting
Non-surgical management after non-surgical repositioning of traumatic anterior dislocation of the shoulder
Non-surgical management after non-surgical repositioning of traumatic anterior dislocation of the shoulder
Oral non-steroidal anti-inflammatory drugs compared with other oral pain killers for sprains, strains and bruises
Oral non-steroidal anti-inflammatory drugs compared with other oral pain killers for sprains, strains and bruises
Platelet-rich therapies for musculoskeletal soft tissue injuries
Platelet-rich therapies for musculoskeletal soft tissue injuries
Regular or selected use of computed tomography (CT) scanning to reduce deaths in people who have a high-energy blunt-traumatic injury
Regular or selected use of computed tomography (CT) scanning to reduce deaths in people who have a high-energy blunt-traumatic injury
Rehabilitation following an injury to the hamstring in adults
Rehabilitation following an injury to the hamstring in adults
Should prophylactic antibiotics be used in patients with penetrating abdominal trauma?
Should prophylactic antibiotics be used in patients with penetrating abdominal trauma?
Splints and other non-surgical methods for treating common injuries of the middle joints of the fingers
Splints and other non-surgical methods for treating common injuries of the middle joints of the fingers
Steroids for acute spinal cord injury
Steroids for acute spinal cord injury
Surgery for unstable trauma patients
Surgery for unstable trauma patients
Surgery versus observation for people with abdominal injury
Surgery versus observation for people with abdominal injury
Surgical approaches for dislocations of the neck bones
Surgical approaches for dislocations of the neck bones
Surgical versus conservative interventions for treating anterior cruciate ligament injuries
Surgical versus conservative interventions for treating anterior cruciate ligament injuries
Treatment of severe blunt pancreatic lesions in children
Treatment of severe blunt pancreatic lesions in children
Treatments for fingertip entrapment injuries in children
Treatments for fingertip entrapment injuries in children
Using ultrasound to aid diagnosis of patients with a 'blunt' injury to the abdomen
Using ultrasound to aid diagnosis of patients with a 'blunt' injury to the abdomen
WOUNDS (14)
Debridement for surgical wounds
Debridement for surgical wounds
Dressings for the prevention of surgical site infection
Dressings for the prevention of surgical site infection
Honey as a topical treatment for acute and chronic wounds
Honey as a topical treatment for acute and chronic wounds
Immediate closure or delayed closure for treating traumatic wounds in the first 24 hours following injury
Immediate closure or delayed closure for treating traumatic wounds in the first 24 hours following injury
Primary closure (immediate stitches) versus delayed closure (delayed stitches) or no closure (no stitches) for traumatic wounds due to mammalian bite
Primary closure (immediate stitches) versus delayed closure (delayed stitches) or no closure (no stitches) for traumatic wounds due to mammalian bite
The effects of water compared with other solutions for wound cleansing
The effects of water compared with other solutions for wound cleansing
Tissue adhesives for closure of surgical skin incisions
Tissue adhesives for closure of surgical skin incisions
UROLOGY AND KIDNEY DISEASES (29)
KIDNEY DISEASES (6)
Hydroxyethyl starch (HES) versus other fluid therapies: effects on kidney function
Hydroxyethyl starch (HES) versus other fluid therapies: effects on kidney function
Is sodium bicarbonate therapy helpful for people with acute kidney problems?
Is sodium bicarbonate therapy helpful for people with acute kidney problems?
Nonsteroidal anti-inflammatory drugs are effective treatment for acute renal colic
Nonsteroidal anti-inflammatory drugs are effective treatment for acute renal colic
UROLOGY (23)
Alpha-blockers for ureteral stones in adult patients with symptoms of stone disease
Alpha-blockers for ureteral stones in adult patients with symptoms of stone disease
Antibiotic prophylaxis for short-term catheter bladder drainage in adults
Antibiotic prophylaxis for short-term catheter bladder drainage in adults
Antibiotic treatment for asymptomatic bacteriuria
Antibiotics for lower urinary tract infection in children
Antibiotics for lower urinary tract infection in children
Fluids and diuretics for treating acute ureteric colic
Fluids and diuretics for treating acute ureteric colic
Increased water intake for preventing urinary stones
Increased water intake for preventing urinary stones
Procalcitonin, C-reactive protein, and erythrocyte sedimentation rate for the diagnosis of acute pyelonephritis in children
Procalcitonin, C-reactive protein, and erythrocyte sedimentation rate for the diagnosis of acute pyelonephritis in children
Screening with urinary dipsticks for reducing morbidity and mortality
Screening with urinary dipsticks for reducing morbidity and mortality
Types of urethral catheters for management of short-term voiding problems in hospitalised adults
Types of urethral catheters for management of short-term voiding problems in hospitalised adults
Urinary alkalisation for uncomplicated urinary tract infections
Urinary alkalisation for uncomplicated urinary tract infections
Urinary catheter policies for long-term bladder drainage
Urinary catheter policies for long-term bladder drainage
Which route of short-term bladder drainage is best for adults in hospital?
Which route of short-term bladder drainage is best for adults in hospital?